Bactrim and Bladder disorder - a phase IV clinical study of FDA data

Summary:

Bladder disorder is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Bladder disorder when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Bladder disorder?

Bladder disorder is found to be associated with 906 drugs and 896 conditions by eHealthMe. Check the latest studies of Bladder disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 76 people (0.09%) have Bladder disorder.

Among these 76 people:

How long have people been on Bactrim when they have Bladder disorder? *

What is the gender of people who have Bladder disorder when taking Bactrim? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Bladder disorder when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Bladder disorder? *

Pain: 16 people, 21.05%
Headache (pain in head): 14 people, 18.42%
Diarrhea: 14 people, 18.42%
Fatigue (feeling of tiredness): 13 people, 17.11%
Acute Kidney Failure: 13 people, 17.11%
Drug Ineffective: 12 people, 15.79%
Depression: 12 people, 15.79%
High Blood Pressure: 11 people, 14.47%
Pain In Extremity: 10 people, 13.16%
Urination - Painful: 10 people, 13.16%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 18.42%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 14.47%
High Blood Pressure: 11 people, 14.47%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 9.21%
Asthma: 6 people, 7.89%
Muscle Spasms (muscle contraction): 4 people, 5.26%
High Blood Cholesterol: 4 people, 5.26%
Hot Flush (sudden feelings of heat): 4 people, 5.26%
Seasonal Allergy (allergic condition due to certain season): 4 people, 5.26%
Pain: 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Bladder disorder?

- Check whether Bladder disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Bladder disorder treatments and more:

Bladder disorder (20,149 reports)

How severe was Bladder disorder and when was it recovered:

Bladder disorder in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Bladder disorder and drugs with ingredients of sulfamethoxazole; trimethoprim (142 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder disorder:

Bladder disorder (906 drugs)

Browse all the conditions that are associated with Bladder disorder:

Bladder disorder (896 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.