Bactrim and Bladder transitional cell carcinoma - a phase IV clinical study of FDA data

Summary:

Bladder transitional cell carcinoma is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Magnesium, and have Mantle cell lymphoma.

The phase IV clinical study analyzes which people have Bladder transitional cell carcinoma when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Bladder transitional cell carcinoma?

Bladder transitional cell carcinoma (types of bladder cancer) is found to be associated with 200 drugs and 229 conditions by eHealthMe. Check the latest studies of Bladder transitional cell carcinoma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 11 people (0.01%) have Bladder transitional cell carcinoma.

Could Bactrim cause Bladder transitional cell carcinoma?

Among these 11 people:

How long have people been on Bactrim when they have Bladder transitional cell carcinoma? *

What is the gender of people who have Bladder transitional cell carcinoma when taking Bactrim? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Bladder transitional cell carcinoma when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Bladder transitional cell carcinoma? *

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 4 people, 36.36%
Viral Infection: 3 people, 27.27%
Second Primary Malignancy (after getting cure a cancer, a new cancer development): 1 person, 9.09%
Metastases To Liver (cancer spreads to liver): 1 person, 9.09%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 9.09%
Haematuria (presence of blood in urine): 1 person, 9.09%
Gastroenteritis Norovirus (inflammation of stomach and intestine caused by norovirus infection): 1 person, 9.09%

What are the existing conditions these people have? *

Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 5 people, 45.45%
Renal Disorder (kidney disease): 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 2 people, 18.18%
Indigestion: 2 people, 18.18%
Itching: 2 people, 18.18%
Multiple Myeloma (cancer of the plasma cells): 2 people, 18.18%
Nasal Dryness (dry nose): 2 people, 18.18%
Stress And Anxiety: 2 people, 18.18%
Nausea And Vomiting: 2 people, 18.18%
Oropharyngeal Pain: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Bladder transitional cell carcinoma?

- Check whether Bladder transitional cell carcinoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Bladder transitional cell carcinoma treatments and more:

Bladder transitional cell carcinoma (3,349 reports)

How severe was Bladder transitional cell carcinoma and when was it recovered:

Bladder transitional cell carcinoma in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Bladder transitional cell carcinoma and drugs with ingredients of sulfamethoxazole; trimethoprim (63 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder transitional cell carcinoma:

Bladder transitional cell carcinoma (200 drugs)

Browse all the conditions that are associated with Bladder transitional cell carcinoma:

Bladder transitional cell carcinoma (229 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.