Bactrim and Lipohypertrophy - a phase IV clinical study of FDA data

Summary:

Lipohypertrophy is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are female, 20-29 old, also take Epivir, and have Hiv infection.

The phase IV clinical study analyzes which people have Lipohypertrophy when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Lipohypertrophy?

Lipohypertrophy (a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin) is found to be associated with 106 drugs and 169 conditions by eHealthMe. Check the latest studies of Lipohypertrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 11 people (0.01%) have Lipohypertrophy.

Among these 11 people:

What is the gender of people who have Lipohypertrophy when taking Bactrim? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Lipohypertrophy when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Lipohypertrophy? *

Suicide Attempt: 5 people, 45.45%
Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 5 people, 45.45%
Sinusitis (inflammation of sinus): 5 people, 45.45%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 45.45%
Pharyngotonsillitis (inflammation of the pharynx and the tonsils): 5 people, 45.45%
Depression: 5 people, 45.45%
Hidradenitis (chronic disease of a type of sweat gland): 4 people, 36.36%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 3 people, 27.27%
Ileus Paralytic (obstruction of the intestine due to paralysis of the intestinal muscles): 3 people, 27.27%
Weakness: 2 people, 18.18%

What are the existing conditions these people have? *

Hiv Infection: 10 people, 90.91%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Depression: 1 person, 9.09%
Cytomegalovirus Mucocutaneous Ulcer (oral ulcers associated with cytomegalovirus infection): 1 person, 9.09%
Anal Cancer: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Lipohypertrophy?

- Check whether Lipohypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Lipohypertrophy treatments and more:

Lipohypertrophy (865 reports)

How severe was Lipohypertrophy and when was it recovered:

Lipohypertrophy in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Lipohypertrophy and drugs with ingredients of sulfamethoxazole; trimethoprim

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lipohypertrophy:

Lipohypertrophy (106 drugs)

Browse all the conditions that are associated with Lipohypertrophy:

Lipohypertrophy (169 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.