Bactrim and Protein total increased - a phase IV clinical study of FDA data

Summary:

Protein total increased is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Zantac, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Protein total increased when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Protein total increased?

Protein total increased is found to be associated with 420 drugs and 438 conditions by eHealthMe. Check the latest studies of Protein total increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 45 people (0.05%) have Protein total increased.

Could Bactrim cause Protein total increased?

Among these 45 people:

How long have people been on Bactrim when they have Protein total increased? *

What is the gender of people who have Protein total increased when taking Bactrim? *

female: 48.84 %
male: 51.16 %

What is the age of people who have Protein total increased when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Protein total increased? *

Fever: 18 people, 40.00%
Fatigue (feeling of tiredness): 12 people, 26.67%
Headache (pain in head): 10 people, 22.22%
Brain Neoplasm (tumour of brain): 9 people, 20.00%
Neoplasm Progression (growth of tumour): 9 people, 20.00%
Injection Site Erythema (redness at injection site): 8 people, 17.78%
Infusion Site Pain: 8 people, 17.78%
Feeling Abnormal: 8 people, 17.78%
Injection Site Irritation: 8 people, 17.78%
Injection Site Pruritus (severe itching at injection site): 8 people, 17.78%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 28.89%
Primary Immunodeficiency Syndrome: 7 people, 15.56%
Hypergammaglobulinaemia (elevated levels of gamma globulin): 5 people, 11.11%
Nausea (feeling of having an urge to vomit): 4 people, 8.89%
Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 3 people, 6.67%
Spinal Muscular Atrophy (wasting of spinal muscles): 2 people, 4.44%
Hiv Infection: 2 people, 4.44%
Chronic Granulomatous Disease (immune system cells are unable to kill some types of bacteria and fungi): 2 people, 4.44%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 2.22%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 2.22%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Protein total increased?

- Check whether Protein total increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Protein total increased treatments and more:

Protein total increased (3,394 reports)

How severe was Protein total increased and when was it recovered:

Protein total increased in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Protein total increased and drugs with ingredients of sulfamethoxazole; trimethoprim (87 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Protein total increased:

Protein total increased (420 drugs)

Browse all the conditions that are associated with Protein total increased:

Protein total increased (438 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.