Bactrim and Throat tightness - a phase IV clinical study of FDA data

Summary:

Throat tightness is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Throat tightness when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Throat tightness?

Throat tightness is found to be associated with 1,231 drugs and 1,408 conditions by eHealthMe. Check the latest studies of Throat tightness.



On Jul, 20, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 91 people (0.11%) have Throat tightness.

Could Bactrim cause Throat tightness?

Among these 91 people:

How long have people been on Bactrim when they have Throat tightness? *

  • < 1 month: 81.82 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 18.18 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Throat tightness when taking Bactrim? *

  • female: 65.48 %
  • male: 34.52 %

What is the age of people who have Throat tightness when taking Bactrim? *

  • 0-1: 0.0 %
  • 2-9: 1.59 %
  • 10-19: 14.29 %
  • 20-29: 9.52 %
  • 30-39: 17.46 %
  • 40-49: 9.52 %
  • 50-59: 14.29 %
  • 60+: 33.33 %

What are other drugs people take besides Bactrim? *

  1. Prednisone: 17 people, 18.68%
  2. Heparin: 15 people, 16.48%
  3. Vitamin D3: 14 people, 15.38%
  4. Acetaminophen: 14 people, 15.38%
  5. Sodium Chloride: 13 people, 14.29%
  6. Diphenhydramine Hydrochloride: 12 people, 13.19%
  7. Tylenol: 12 people, 13.19%
  8. Protonix: 12 people, 13.19%
  9. Zofran: 12 people, 13.19%
  10. Vitamin B: 11 people, 12.09%

What are other side effects people have besides Throat tightness? *

  1. Dyspnea (difficult or laboured breathing): 40 people, 43.96%
  2. Fatigue (feeling of tiredness): 23 people, 25.27%
  3. Itching: 22 people, 24.18%
  4. Rashes (redness): 22 people, 24.18%
  5. Chest Pain: 21 people, 23.08%
  6. Dizziness: 18 people, 19.78%
  7. Nausea (feeling of having an urge to vomit): 16 people, 17.58%
  8. Pain: 15 people, 16.48%
  9. Urticaria (rash of round, red welts on the skin that itch intensely): 14 people, 15.38%
  10. Headache (pain in head): 14 people, 15.38%

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 14 people, 15.38%
  2. Multiple Myeloma (cancer of the plasma cells): 7 people, 7.69%
  3. Dehydration (dryness resulting from the removal of water): 6 people, 6.59%
  4. Immunodeficiency: 5 people, 5.49%
  5. Type 2 Diabetes: 4 people, 4.40%
  6. Thrombocytopenia (decrease of platelets in blood): 4 people, 4.40%
  7. Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 4 people, 4.40%
  8. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 4.40%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 3.30%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 3.30%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Throat tightness?

- Check whether Throat tightness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Throat tightness treatments and more:

How severe was Throat tightness and when was it recovered:

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Throat tightness:

Browse all the conditions that are associated with Throat tightness:


How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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