Bactrim and Vaginal bleeding between periods - a phase IV clinical study of FDA data

Summary:

Vaginal bleeding between periods is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are 10-19 old, have been taking the drug for < 1 month also take Retrovir, and have Hiv infection.

The phase IV clinical study analyzes which people have Vaginal bleeding between periods when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Vaginal bleeding between periods?

Vaginal bleeding between periods is found to be associated with 577 drugs and 1,467 conditions by eHealthMe. Check the latest studies of Vaginal bleeding between periods.

On May, 27, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 40 people (0.05%) have Vaginal bleeding between periods.

Could Bactrim cause Vaginal bleeding between periods?

Among these 40 people:

How long have people been on Bactrim when they have Vaginal bleeding between periods? *

What is the age of people who have Vaginal bleeding between periods when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Vaginal bleeding between periods? *

Anaemia (lack of blood): 9 people, 22.50%
Nausea (feeling of having an urge to vomit): 6 people, 15.00%
Headache (pain in head): 6 people, 15.00%
Haemoglobin Decreased: 6 people, 15.00%
Birth Control: 5 people, 12.50%
Premature Labor: 5 people, 12.50%
Abdominal Pain: 4 people, 10.00%
Oedema (fluid collection in tissue): 4 people, 10.00%
Renal Impairment (severely reduced kidney function): 4 people, 10.00%
Complications Of Maternal Exposure To Therapeutic Drugs: 4 people, 10.00%

What are the existing conditions these people have? *

Hiv Infection: 6 people, 15.00%
Birth Control: 5 people, 12.50%
High Blood Cholesterol: 4 people, 10.00%
Hiv Test Positive: 4 people, 10.00%
Anaemia (lack of blood): 4 people, 10.00%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 4 people, 10.00%
High Blood Pressure: 4 people, 10.00%
Acidosis (build-up of carbon dioxide in the blood): 4 people, 10.00%
Oral Candidiasis (fungal infection of mouth): 4 people, 10.00%
Asthma: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Vaginal bleeding between periods?

- Check whether Vaginal bleeding between periods is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Vaginal bleeding between periods treatments and more:

Vaginal bleeding between periods (26,954 reports)

How severe was Vaginal bleeding between periods and when was it recovered:

Vaginal bleeding between periods in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Vaginal bleeding between periods and drugs with ingredients of sulfamethoxazole; trimethoprim (62 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal bleeding between periods:

Vaginal bleeding between periods (577 drugs)

Browse all the conditions that are associated with Vaginal bleeding between periods:

Vaginal bleeding between periods (1,467 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.