Bactrim and Xerosis - a phase IV clinical study of FDA data

Summary:

Xerosis is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Prohance, and have Headache.

The phase IV clinical study analyzes which people have Xerosis when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Xerosis?

Xerosis (abnormal dryness of the skin or mucus membranes) is found to be associated with 192 drugs and 559 conditions by eHealthMe. Check the latest studies of Xerosis.

On Jul, 14, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 27 people (0.03%) have Xerosis.

Among these 27 people:

How long have people been on Bactrim when they have Xerosis? *

What is the gender of people who have Xerosis when taking Bactrim? *

female: 45.83 %
male: 54.17 %

What is the age of people who have Xerosis when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Xerosis? *

Pain In Extremity: 11 people, 40.74%
Itching: 9 people, 33.33%
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 7 people, 25.93%
Skin Exfoliation (removal of the oldest dead skin cells): 7 people, 25.93%
Skin Tightness: 7 people, 25.93%
Rashes (redness): 6 people, 22.22%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 5 people, 18.52%
Myocardial Fibrosis (a condition in which the heart's muscle cells are impaired): 5 people, 18.52%
Metaplasia (change in the type of adult cells in a tissue to a form abnormal for that tissue): 5 people, 18.52%
Skin Induration (an abnormally hard spot or area on the skin): 5 people, 18.52%

What are the existing conditions these people have? *

Renal Osteodystrophy (a bone disease occurs when the kidneys fail to maintain the proper levels of calcium and phosphorus in the blood): 3 people, 11.11%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 11.11%
Lymphoma (cancer that begins in immune system cells): 3 people, 11.11%
Joint Pain: 3 people, 11.11%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 11.11%
Headache (pain in head): 3 people, 11.11%
Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 7.41%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 7.41%
Asthma: 2 people, 7.41%
Catheter Related Complication: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Xerosis?

- Check whether Xerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Xerosis treatments and more:

Xerosis (1,746 reports)

How severe was Xerosis and when was it recovered:

Xerosis in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Xerosis and drugs with ingredients of sulfamethoxazole; trimethoprim (38 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Xerosis:

Xerosis (192 drugs)

Browse all the conditions that are associated with Xerosis:

Xerosis (559 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.