Belladonna and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Belladonna (belladonna), especially for people who are male, 40-49 old, also take Prednisone, and have Migraine.

The phase IV clinical study analyzes which people have Insomnia when taking Belladonna. It is created by eHealthMe based on reports of 1,002 people who have side effects when taking Belladonna from the FDA, and is updated regularly.

What is Belladonna?

Belladonna has active ingredients of belladonna. It is often used in irritable bowel syndrome. eHealthMe is studying from 1,043 Belladonna users. Check the latest studies of Belladonna.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,116 drugs and 5,173 conditions by eHealthMe. Check the latest studies of Insomnia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

1,002 people reported to have side effects when taking Belladonna.
Among them, 30 people (2.99%) have Insomnia.

Could Belladonna cause Insomnia?

Among these 30 people:

What is the gender of people who have Insomnia when taking Belladonna? *

  • female: 32.14 %
  • male: 67.86 %

What is the age of people who have Insomnia when taking Belladonna? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.35 %
  • 40-49: 47.83 %
  • 50-59: 8.7 %
  • 60+: 39.13 %

What are other drugs people take besides Belladonna? *

  1. Prednisone: 13 people, 43.33%
  2. Ibuprofen: 12 people, 40.00%
  3. Voltaren: 12 people, 40.00%
  4. Lamotrigine: 11 people, 36.67%
  5. Maxalt: 11 people, 36.67%
  6. Zomig: 11 people, 36.67%
  7. Botox: 11 people, 36.67%
  8. Topiramate: 11 people, 36.67%
  9. Acetaminophen: 11 people, 36.67%
  10. Relpax: 11 people, 36.67%

What are other side effects people have besides Insomnia? *

  1. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 15 people, 50.00%
  2. Diarrhea: 7 people, 23.33%
  3. Stress And Anxiety: 6 people, 20.00%
  4. Joint Pain: 6 people, 20.00%
  5. Memory Loss: 5 people, 16.67%
  6. Weakness: 5 people, 16.67%
  7. Dizziness: 4 people, 13.33%
  8. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 13.33%
  9. Confusional State: 4 people, 13.33%
  10. Nausea (feeling of having an urge to vomit): 4 people, 13.33%

What are the existing conditions these people have? *

  1. Migraine (headache): 11 people, 36.67%
  2. Carcinoid Tumor: 4 people, 13.33%
  3. Pain: 3 people, 10.00%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.00%
  5. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 6.67%
  6. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 2 people, 6.67%
  7. Bronchopneumopathy: 1 person, 3.33%
  8. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 1 person, 3.33%
  9. Bipolar Disorder (mood disorder): 1 person, 3.33%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Belladonna and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Belladonna:

Insomnia treatments and more:

How severe was Insomnia and when was it recovered:

Expand to all the drugs that have ingredients of belladonna:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Belladonna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Browse all the conditions that are associated with Insomnia:


How the study uses the data?

The study uses data from the FDA. It is based on belladonna (the active ingredients of Belladonna) and Belladonna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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