Belsomra and Drug hypersensitivity - a phase IV clinical study of FDA data

Summary:

Drug hypersensitivity is reported as a side effect among people who take Belsomra (suvorexant), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Narcolepsy.

The phase IV clinical study analyzes which people have Drug hypersensitivity when taking Belsomra. It is created by eHealthMe based on reports of 12,886 people who have side effects when taking Belsomra from the FDA, and is updated regularly.

What is Belsomra?

Belsomra has active ingredients of suvorexant. It is often used in insomnia. eHealthMe is studying from 12,961 Belsomra users. Check the latest studies of Belsomra.

What is Drug hypersensitivity?

Drug hypersensitivity is found to be associated with 2,480 drugs and 2,340 conditions by eHealthMe. Check the latest studies of Drug hypersensitivity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

12,886 people reported to have side effects when taking Belsomra.
Among them, 41 people (0.32%) have Drug hypersensitivity.

Could Belsomra cause Drug hypersensitivity?

Among these 41 people:

How long have people been on Belsomra when they have Drug hypersensitivity? *

What is the gender of people who have Drug hypersensitivity when taking Belsomra? *

female: 76.32 %
male: 23.68 %

What is the age of people who have Drug hypersensitivity when taking Belsomra? *

What are other drugs people take besides Belsomra? *

What are other side effects people have besides Drug hypersensitivity? *

Pain: 6 people, 14.63%
Fatigue (feeling of tiredness): 4 people, 9.76%
Drug Ineffective: 4 people, 9.76%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 4 people, 9.76%
Cough: 4 people, 9.76%
Drowsiness: 4 people, 9.76%
Loss Of Consciousness: 3 people, 7.32%
Itching: 3 people, 7.32%
Hypotension (abnormally low blood pressure): 3 people, 7.32%
Headache (pain in head): 3 people, 7.32%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 12.20%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 7.32%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 2 people, 4.88%
Stress And Anxiety: 2 people, 4.88%
Sleep Disorder: 2 people, 4.88%
Depression: 2 people, 4.88%
Dyslipidaemia (abnormal amount of lipids): 2 people, 4.88%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 2 people, 4.88%
Headache (pain in head): 1 person, 2.44%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Belsomra and have Drug hypersensitivity?

- Check whether Drug hypersensitivity is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Belsomra:

Belsomra (12,961 reports)

Browse all side effects of Belsomra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug hypersensitivity:

Drug hypersensitivity (2,480 drugs)

Browse all the conditions that are associated with Drug hypersensitivity:

Drug hypersensitivity (2,340 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on suvorexant (the active ingredients of Belsomra) and Belsomra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.