Bendamustine and Upper gastrointestinal haemorrhage - a phase IV clinical study of FDA data

Summary:

Upper gastrointestinal haemorrhage is reported as a side effect among people who take Bendamustine (bendamustine), especially for people who are male, 50-59 old, also take Heparin, and have Non-hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Upper gastrointestinal haemorrhage when taking Bendamustine. It is created by eHealthMe based on reports of 9,503 people who have side effects when taking Bendamustine from the FDA, and is updated regularly.

What is Bendamustine?

Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.

What is Upper gastrointestinal haemorrhage?

Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding) is found to be associated with 1,022 drugs and 1,017 conditions by eHealthMe. Check the latest studies of Upper gastrointestinal haemorrhage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

9,503 people reported to have side effects when taking Bendamustine.
Among them, 11 people (0.12%) have Upper gastrointestinal haemorrhage.

Could Bendamustine cause Upper gastrointestinal haemorrhage?

Among these 11 people:

What is the gender of people who have Upper gastrointestinal haemorrhage when taking Bendamustine? *

female: 0.0 %
male: 100 %

What is the age of people who have Upper gastrointestinal haemorrhage when taking Bendamustine? *

What are other drugs people take besides Bendamustine? *

What are other side effects people have besides Upper gastrointestinal haemorrhage? *

Tumor: 2 people, 18.18%
Varices Oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach): 1 person, 9.09%
Lymphadenopathy Mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs): 1 person, 9.09%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 9.09%
Anaemia (lack of blood): 1 person, 9.09%
Disease Recurrence: 1 person, 9.09%
Fever: 1 person, 9.09%
Gastric Cancer (stomach cancer): 1 person, 9.09%
Gastric Mucosal Lesion (lesion of stomach mucous membrane): 1 person, 9.09%
Gastric Ulcer (stomach ulcer): 1 person, 9.09%

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 9 people, 81.82%
Nausea (feeling of having an urge to vomit): 8 people, 72.73%
Neck Pain: 7 people, 63.64%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 63.64%
High Blood Pressure: 7 people, 63.64%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 63.64%
Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 18.18%
Oropharyngeal Pain: 1 person, 9.09%
Mood Swings (an extreme or rapid change in mood): 1 person, 9.09%
Cough: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Bendamustine and have Upper gastrointestinal haemorrhage?

- Check whether Upper gastrointestinal haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bendamustine:

Bendamustine (9,508 reports)

Browse all side effects of Bendamustine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Upper gastrointestinal haemorrhage:

Upper gastrointestinal haemorrhage (1,022 drugs)

Browse all the conditions that are associated with Upper gastrointestinal haemorrhage:

Upper gastrointestinal haemorrhage (1,017 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bendamustine (the active ingredients of Bendamustine) and Bendamustine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.