Bendeka and Hypotension - a phase IV clinical study of FDA data

Summary:

Hypotension is reported as a side effect among people who take Bendeka (bendamustine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Rituxan, and have Mantle cell lymphoma.

The phase IV clinical study analyzes which people have Hypotension when taking Bendeka. It is created by eHealthMe based on reports of 588 people who have side effects when taking Bendeka from the FDA, and is updated regularly.

What is Bendeka?

Bendeka has active ingredients of bendamustine hydrochloride. eHealthMe is studying from 591 Bendeka users. Check the latest studies of Bendeka.

What is Hypotension?

Hypotension (abnormally low blood pressure) is found to be associated with 3,352 drugs and 4,763 conditions by eHealthMe. Check the latest studies of Hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 11, 2026

588 people reported to have side effects when taking Bendeka.
Among them, 22 people (3.74%) have Hypotension.

Could Bendeka cause Hypotension?

Among these 22 people:

How long have people been on Bendeka when they have Hypotension? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypotension when taking Bendeka? *

  • female: 15.79 %
  • male: 84.21 %

What is the age of people who have Hypotension when taking Bendeka? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.14 %
  • 50-59: 7.14 %
  • 60+: 85.71 %

What are other drugs people take besides Bendeka? *

  1. Rituxan: 19 people, 86.36%
  2. Neulasta: 8 people, 36.36%
  3. Sertraline: 7 people, 31.82%
  4. Benadryl: 5 people, 22.73%
  5. Imbruvica: 4 people, 18.18%
  6. Zofran: 3 people, 13.64%
  7. Pepcid: 3 people, 13.64%
  8. Pantoprazole: 3 people, 13.64%
  9. Ninlaro: 2 people, 9.09%
  10. Bactrim Ds: 2 people, 9.09%

What are other side effects people have besides Hypotension? *

  1. Drug Ineffective: 7 people, 31.82%
  2. Febrile Neutropenia (fever with reduced white blood cells): 7 people, 31.82%
  3. Rashes (redness): 5 people, 22.73%
  4. Skin Blushing/flushing (a sudden reddening of the face, neck): 4 people, 18.18%
  5. Urticaria (rash of round, red welts on the skin that itch intensely): 4 people, 18.18%
  6. Weight Decreased: 3 people, 13.64%
  7. Arrhythmias (irregular heartbeat): 3 people, 13.64%
  8. Dehydration (dryness resulting from the removal of water): 3 people, 13.64%
  9. Diarrhea: 3 people, 13.64%
  10. Dizziness Postural: 3 people, 13.64%

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 13.64%
  2. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 3 people, 13.64%
  3. Nausea (feeling of having an urge to vomit): 2 people, 9.09%
  4. Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
  5. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 9.09%
  6. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 4.55%
  7. Burkitt Lymphoma (cancer of the lymphatic system): 1 person, 4.55%
  8. B-Cell Lymphoma Recurrent (blood cancer affecting b cells-recurrent): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Bendeka and have Hypotension?

- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bendeka:

Hypotension treatments and more:

How severe was Hypotension and when was it recovered:

Expand to all the drugs that have ingredients of bendamustine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bendeka:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension:

Browse all the conditions that are associated with Hypotension:


How the study uses the data?

The study uses data from the FDA. It is based on bendamustine hydrochloride (the active ingredients of Bendeka) and Bendeka (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: