Benicar hct and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Benicar hct (hydrochlorothiazide; olmesartan medoxomil), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Benicar, and have Multiple myeloma.

The study is created by eHealthMe based on reports of 10,269 people who have side effects when taking Benicar hct from the FDA, and is updated regularly.

What is Benicar hct?

Benicar hct has active ingredients of hydrochlorothiazide; olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 10,919 Benicar hct users. Check the latest studies of Benicar hct.



On Jul, 15, 2026

10,269 people reported to have side effects when taking Benicar hct.
Among them, 57 people (0.56%) died.

Could Benicar hct cause Death?

Among these 57 people:

How long have people been on Benicar hct when they died? *

  • < 1 month: 25.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 8.33 %
  • 1 - 2 years: 8.33 %
  • 2 - 5 years: 41.67 %
  • 5 - 10 years: 8.33 %
  • 10+ years: 8.33 %

What is the gender of people who died when taking Benicar hct? *

  • female: 55.56 %
  • male: 44.44 %

What is the age of people who died when taking Benicar hct? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.35 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 17.39 %
  • 60+: 78.26 %

What are other drugs people take besides Benicar hct? *

  1. Benicar: 15 people, 26.32%
  2. Singulair: 9 people, 15.79%
  3. Metformin: 7 people, 12.28%
  4. Aspirin: 7 people, 12.28%
  5. Crestor: 7 people, 12.28%
  6. Nexium: 6 people, 10.53%
  7. Lipitor: 6 people, 10.53%
  8. Symbicort: 6 people, 10.53%
  9. Bystolic: 5 people, 8.77%
  10. Lyrica: 5 people, 8.77%

What are other side effects people have before they died? *

  1. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 6 people, 10.53%
  2. Dizziness: 5 people, 8.77%
  3. Anaemia (lack of blood): 5 people, 8.77%
  4. Fainting (loss of consciousness and postural tone): 5 people, 8.77%
  5. Nausea And Vomiting: 4 people, 7.02%
  6. Nausea (feeling of having an urge to vomit): 4 people, 7.02%
  7. Head Injury: 4 people, 7.02%
  8. Fatigue (feeling of tiredness): 4 people, 7.02%
  9. Pain: 4 people, 7.02%
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 5.26%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.02%
  2. Idiopathic Pulmonary Fibrosis (chronic lung disease): 4 people, 7.02%
  3. Multiple Myeloma (cancer of the plasma cells): 4 people, 7.02%
  4. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 5.26%
  5. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 5.26%
  6. Erection Problems: 2 people, 3.51%
  7. Asthma: 2 people, 3.51%
  8. Hiv Infection: 2 people, 3.51%
  9. Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 3.51%
  10. Depression: 2 people, 3.51%

* Approximation only. Some reports may have incomplete information.



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Benicar hct:

Expand to all the drugs that have ingredients of hydrochlorothiazide; olmesartan medoxomil:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Benicar hct:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Browse all the conditions that are associated with Death:

  • Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; olmesartan medoxomil (the active ingredients of Benicar hct) and Benicar hct (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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