Bentyl and Cystitis interstitial - a phase IV clinical study of FDA data

Summary:

Cystitis interstitial is reported as a side effect among people who take Bentyl (dicyclomine hydrochloride), especially for people who are female, 40-49 old, also take Singulair, and have Cataplexy.

The phase IV clinical study analyzes which people have Cystitis interstitial when taking Bentyl. It is created by eHealthMe based on reports of 10,046 people who have side effects when taking Bentyl from the FDA, and is updated regularly.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.

What is Cystitis interstitial?

Cystitis interstitial (unknown cause characterized by bladder pain) is found to be associated with 332 drugs and 439 conditions by eHealthMe. Check the latest studies of Cystitis interstitial.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

10,046 people reported to have side effects when taking Bentyl.
Among them, 11 people (0.11%) have Cystitis interstitial.

Could Bentyl cause Cystitis interstitial?

Among these 11 people:

What is the gender of people who have Cystitis interstitial when taking Bentyl? *

female: 100 %
male: 0.0 %

What is the age of people who have Cystitis interstitial when taking Bentyl? *

What are other drugs people take besides Bentyl? *

What are other side effects people have besides Cystitis interstitial? *

Nausea And Vomiting: 7 people, 63.64%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 5 people, 45.45%
Therapeutic Response Decreased (less preventive response): 4 people, 36.36%
Poor Quality Sleep: 4 people, 36.36%
Neuralgia (pain in one or more nerves): 4 people, 36.36%
Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 36.36%
Anaemia (lack of blood): 3 people, 27.27%
Migraine (headache): 3 people, 27.27%
Drug Ineffective: 3 people, 27.27%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 27.27%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 45.45%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 45.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 36.36%
Stress And Anxiety: 3 people, 27.27%
Migraine (headache): 3 people, 27.27%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 27.27%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 18.18%
Muscle Spasms (muscle contraction): 2 people, 18.18%
Hypersensitivity: 2 people, 18.18%
Asthma: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Bentyl and have Cystitis interstitial?

- Check whether Cystitis interstitial is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bentyl:

Bentyl (10,754 reports)

Browse all side effects of Bentyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cystitis interstitial:

Cystitis interstitial (332 drugs)

Browse all the conditions that are associated with Cystitis interstitial:

Cystitis interstitial (439 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dicyclomine hydrochloride (the active ingredients of Bentyl) and Bentyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.