Benzonatate and Hypogeusia - a phase IV clinical study of FDA data

Summary:

Hypogeusia is reported as a side effect among people who take Benzonatate (benzonatate), especially for people who are female, 60+ old, also take Metformin, and have Renal cell carcinoma.

The phase IV clinical study analyzes which people have Hypogeusia when taking Benzonatate. It is created by eHealthMe based on reports of 16,665 people who have side effects when taking Benzonatate from the FDA, and is updated regularly.

What is Benzonatate?

Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 17,274 Benzonatate users. Check the latest studies of Benzonatate.

What is Hypogeusia?

Hypogeusia (reduced ability to taste things (to taste sweet, sour, bitter, or salty substances)) is found to be associated with 262 drugs and 388 conditions by eHealthMe. Check the latest studies of Hypogeusia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

16,665 people reported to have side effects when taking Benzonatate.
Among them, 11 people (0.07%) have Hypogeusia.

Among these 11 people:

What is the gender of people who have Hypogeusia when taking Benzonatate? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Hypogeusia when taking Benzonatate? *

What are other drugs people take besides Benzonatate? *

Metformin: 6 people, 54.55%
Zofran: 4 people, 36.36%
Vitamin D: 4 people, 36.36%
Sutent: 4 people, 36.36%
Compazine: 4 people, 36.36%
Hydrocodone Bitartrate And Acetaminophen: 4 people, 36.36%
Imodium A-D: 3 people, 27.27%
Ambien: 2 people, 18.18%
Ativan: 2 people, 18.18%
Bactrim: 2 people, 18.18%

What are other side effects people have besides Hypogeusia? *

Nausea (feeling of having an urge to vomit): 5 people, 45.45%
Constipation: 5 people, 45.45%
Diarrhea: 5 people, 45.45%
Thrombocytopenia (decrease of platelets in blood): 5 people, 45.45%
Fatigue (feeling of tiredness): 5 people, 45.45%
Flatulence (flatus expelled through the anus): 4 people, 36.36%
Hyperkeratosis (thickening of the outer layer of the skin): 4 people, 36.36%
Hyperaesthesia: 4 people, 36.36%
Hair Loss: 4 people, 36.36%
Hair Color Changes: 4 people, 36.36%

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 4 people, 36.36%
Metastases To Lung (cancer spreads to lung): 2 people, 18.18%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 18.18%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 18.18%
Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 9.09%
Acne (skin problems that cause pimples): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Benzonatate and have Hypogeusia?

- Check whether Hypogeusia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Benzonatate:

Benzonatate (17,274 reports)

Hypogeusia treatments and more:

Hypogeusia (2,199 reports)

Browse all side effects of Benzonatate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypogeusia:

Hypogeusia (262 drugs)

Browse all the conditions that are associated with Hypogeusia:

Hypogeusia (388 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on benzonatate (the active ingredients of Benzonatate) and Benzonatate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.