Betagan and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Betagan (levobunolol hydrochloride), especially for people who are female, 20-29 old, also take Piroxicam, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Betagan. It is created by eHealthMe based on reports of 449 people who have side effects when taking Betagan from the FDA, and is updated regularly.

What is Betagan?

Betagan has active ingredients of levobunolol hydrochloride. eHealthMe is studying from 453 Betagan users. Check the latest studies of Betagan.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,615 drugs and 2,599 conditions by eHealthMe. Check the latest studies of Hypothyroidism.



On Jul, 16, 2026

449 people reported to have side effects when taking Betagan.
Among them, 14 people (3.12%) have Hypothyroidism.

Could Betagan cause Hypothyroidism?

Among these 14 people:

What is the gender of people who have Hypothyroidism when taking Betagan? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Hypothyroidism when taking Betagan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 100 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Betagan? *

  1. Zoloft: 14 people, 100.00%
  2. Synthroid: 14 people, 100.00%
  3. Provera: 14 people, 100.00%
  4. Piroxicam: 14 people, 100.00%
  5. Clonazepam: 12 people, 85.71%
  6. Loratadine: 10 people, 71.43%
  7. Paroxetine: 5 people, 35.71%
  8. Midazolam Hydrochloride: 2 people, 14.29%
  9. Midazolam: 2 people, 14.29%

What are other side effects people have besides Hypothyroidism? *

  1. Abdominal Pain: 14 people, 100.00%
  2. Galactorrhea (secretion of breast milk in men): 14 people, 100.00%
  3. Headache (pain in head): 14 people, 100.00%
  4. Weight Decreased: 14 people, 100.00%
  5. Eyelid Ptosis (falling of the upper or lower eyelid): 14 people, 100.00%
  6. Euphoric Mood (excessively happy but may become angry or irritable): 14 people, 100.00%
  7. Insomnia (sleeplessness): 14 people, 100.00%
  8. Irritability: 14 people, 100.00%
  9. Drowsiness: 14 people, 100.00%
  10. Dizziness: 14 people, 100.00%

What are the existing conditions these people have? *

  1. Uterine Haemorrhage (uterine bleeding): 14 people, 100.00%
  2. Bipolar Disorder (mood disorder): 14 people, 100.00%
  3. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 28.57%
  4. Depression: 4 people, 28.57%
  5. Panic Reaction: 3 people, 21.43%
  6. Stress And Anxiety: 2 people, 14.29%
  7. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Betagan and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Betagan:

Hypothyroidism treatments and more:

How severe was Hypothyroidism and when was it recovered:

Expand to all the drugs that have ingredients of levobunolol hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Betagan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Browse all the conditions that are associated with Hypothyroidism:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levobunolol hydrochloride (the active ingredients of Betagan) and Betagan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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