Bextra and Vitreous detachment - a phase IV clinical study of FDA data

Summary:

Vitreous detachment is reported as a side effect among people who take Bextra (valdecoxib), especially for people who are female, 50-59 old, also take Aredia, and have Osteoporosis.

The phase IV clinical study analyzes which people have Vitreous detachment when taking Bextra. It is created by eHealthMe based on reports of 20,982 people who have side effects when taking Bextra from the FDA, and is updated regularly.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

What is Vitreous detachment?

Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina) is found to be associated with 410 drugs and 457 conditions by eHealthMe. Check the latest studies of Vitreous detachment.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

20,982 people reported to have side effects when taking Bextra.
Among them, 37 people (0.18%) have Vitreous detachment.

Among these 37 people:

What is the gender of people who have Vitreous detachment when taking Bextra? *

female: 100 %
male: 0.0 %

What is the age of people who have Vitreous detachment when taking Bextra? *

What are other drugs people take besides Bextra? *

What are other side effects people have besides Vitreous detachment? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 33 people, 89.19%
Osteomyelitis (infection of bone): 32 people, 86.49%
Foot Fracture: 31 people, 83.78%
Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 31 people, 83.78%
Exostosis (formation of new bone on the surface of a bone): 31 people, 83.78%
Spinal Osteoarthritis (joint cartilage loss in spine): 31 people, 83.78%
Swelling: 31 people, 83.78%
Osteopenia (a condition where bone mineral density is lower than normal): 30 people, 81.08%
Osteoporosis (bones weak and more likely to break): 29 people, 78.38%
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs): 29 people, 78.38%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 27 people, 72.97%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 25 people, 67.57%
Thrombocytopenia (decrease of platelets in blood): 11 people, 29.73%
Breast Cancer: 6 people, 16.22%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 13.51%
Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 10.81%
Hypersensitivity: 4 people, 10.81%
High Blood Pressure: 4 people, 10.81%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 10.81%
Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Bextra and have Vitreous detachment?

- Check whether Vitreous detachment is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bextra:

Bextra (20,994 reports)

Browse all side effects of Bextra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vitreous detachment:

Vitreous detachment (410 drugs)

Browse all the conditions that are associated with Vitreous detachment:

Vitreous detachment (457 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on valdecoxib (the active ingredients of Bextra) and Bextra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.