Biotin and Hypotonia - a phase IV clinical study of FDA data

Summary:

Hypotonia is reported as a side effect among people who take Biotin (biotin), especially for people who are female, 40-49 old, also take Magnesium, and have Bladder irritation.

The phase IV clinical study analyzes which people have Hypotonia when taking Biotin. It is created by eHealthMe based on reports of 33,728 people who have side effects when taking Biotin from the FDA, and is updated regularly.

What is Biotin?

Biotin has active ingredients of biotin. It is often used in hair loss. eHealthMe is studying from 35,393 Biotin users. Check the latest studies of Biotin.

What is Hypotonia?

Hypotonia (low muscle tone) is found to be associated with 826 drugs and 1,770 conditions by eHealthMe. Check the latest studies of Hypotonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

33,728 people reported to have side effects when taking Biotin.
Among them, 18 people (0.05%) have Hypotonia.

Among these 18 people:

What is the gender of people who have Hypotonia when taking Biotin? *

female: 94.12 %
male: 5.88 %

What is the age of people who have Hypotonia when taking Biotin? *

What are other drugs people take besides Biotin? *

Acetaminophen: 7 people, 38.89%
Magnesium: 7 people, 38.89%
Ocrevus: 6 people, 33.33%
Azelastine Hydrochloride: 4 people, 22.22%
Carafate: 4 people, 22.22%
Dicyclomine Hydrochloride: 4 people, 22.22%
Diphenhydramine Hydrochloride: 4 people, 22.22%
Vitamin B12: 4 people, 22.22%
Fludrocortisone Acetate: 4 people, 22.22%
Gabapentin: 4 people, 22.22%

What are other side effects people have besides Hypotonia? *

Weakness: 10 people, 55.56%
Muscle Spasms (muscle contraction): 8 people, 44.44%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 7 people, 38.89%
Drug Ineffective: 6 people, 33.33%
Nasopharyngitis (inflammation of the nasopharynx): 6 people, 33.33%
Gait Disturbance: 6 people, 33.33%
Pain: 6 people, 33.33%
Dyspnea (difficult or laboured breathing): 6 people, 33.33%
Intervertebral Disc Protrusion (spinal disc protrusion): 6 people, 33.33%
Pneumonia: 6 people, 33.33%

What are the existing conditions these people have? *

Bladder Irritation: 6 people, 33.33%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 22.22%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 22.22%
Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 11.11%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.11%
Birth Control: 2 people, 11.11%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.56%
Androgenetic Alopecia (common form of hair loss): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Biotin and have Hypotonia?

- Check whether Hypotonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Biotin:

Biotin (35,393 reports)

Hypotonia treatments and more:

Hypotonia (14,614 reports)

Browse all side effects of Biotin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotonia:

Hypotonia (826 drugs)

Browse all the conditions that are associated with Hypotonia:

Hypotonia (1,770 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on biotin (the active ingredients of Biotin) and Biotin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.