Biotin and Synovial rupture - a phase IV clinical study of FDA data

Summary:

Synovial rupture is reported as a side effect among people who take Biotin (biotin), especially for people who are female, 50-59 old, also take Crestor, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Synovial rupture when taking Biotin. It is created by eHealthMe based on reports of 33,728 people who have side effects when taking Biotin from the FDA, and is updated regularly.

What is Biotin?

Biotin has active ingredients of biotin. It is often used in hair loss. eHealthMe is studying from 35,393 Biotin users. Check the latest studies of Biotin.

What is Synovial rupture?

Synovial rupture (tear of synovial membrane of joint) is found to be associated with 117 drugs and 156 conditions by eHealthMe. Check the latest studies of Synovial rupture.



On Jul, 21, 2026

33,728 people reported to have side effects when taking Biotin.
Among them, 24 people (0.07%) have Synovial rupture.

Could Biotin cause Synovial rupture?

Among these 24 people:

What is the gender of people who have Synovial rupture when taking Biotin? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Synovial rupture when taking Biotin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 86.36 %
  • 60+: 13.64 %

What are other drugs people take besides Biotin? *

  1. Crestor: 21 people, 87.50%
  2. Zometa: 20 people, 83.33%
  3. Synthroid: 20 people, 83.33%
  4. Lasix: 20 people, 83.33%
  5. Claritin: 20 people, 83.33%
  6. Aredia: 20 people, 83.33%
  7. Selenium: 20 people, 83.33%
  8. Premarin: 20 people, 83.33%
  9. Imdur: 20 people, 83.33%
  10. Zestril: 20 people, 83.33%

What are other side effects people have besides Synovial rupture? *

  1. Synovial Cyst (cyst of joint filled with synovial fluid): 23 people, 95.83%
  2. Pneumonia: 22 people, 91.67%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 22 people, 91.67%
  4. Depression: 20 people, 83.33%
  5. Drug Hypersensitivity: 20 people, 83.33%
  6. Dyspnea Exertional: 20 people, 83.33%
  7. Ejection Fraction Decreased (systolic heart failure): 20 people, 83.33%
  8. Electrocardiogram Qrs Complex Abnormal: 20 people, 83.33%
  9. Electrocardiogram T Wave Inversion: 20 people, 83.33%
  10. Emotional Distress: 20 people, 83.33%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 20 people, 83.33%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.50%
  3. Weight Decreased: 1 person, 4.17%
  4. Tumor: 1 person, 4.17%
  5. Pain: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Biotin and have Synovial rupture?

- Check whether Synovial rupture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Biotin:

Synovial rupture treatments and more:

How severe was Synovial rupture and when was it recovered:

Expand to all the drugs that have ingredients of biotin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Biotin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Synovial rupture:

Browse all the conditions that are associated with Synovial rupture:


How the study uses the data?

The study uses data from the FDA. It is based on biotin (the active ingredients of Biotin) and Biotin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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