Biotin and Withdrawal syndrome - a phase IV clinical study of FDA data

Summary:

Withdrawal syndrome is reported as a side effect among people who take Biotin (biotin), especially for people who are female, 60+ old, also take Vitamin D3, and have Pain.

The phase IV clinical study analyzes which people have Withdrawal syndrome when taking Biotin. It is created by eHealthMe based on reports of 33,728 people who have side effects when taking Biotin from the FDA, and is updated regularly.

What is Biotin?

Biotin has active ingredients of biotin. It is often used in hair loss. eHealthMe is studying from 35,393 Biotin users. Check the latest studies of Biotin.

What is Withdrawal syndrome?

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) is found to be associated with 1,003 drugs and 1,484 conditions by eHealthMe. Check the latest studies of Withdrawal syndrome.

On Jul, 16, 2026

33,728 people reported to have side effects when taking Biotin.
Among them, 99 people (0.29%) have Withdrawal syndrome.

Among these 99 people:

What is the gender of people who have Withdrawal syndrome when taking Biotin? *

female: 96.74 %
male: 3.26 %

What is the age of people who have Withdrawal syndrome when taking Biotin? *

What are other drugs people take besides Biotin? *

What are other side effects people have besides Withdrawal syndrome? *

Nausea (feeling of having an urge to vomit): 31 people, 31.31%
Headache (pain in head): 21 people, 21.21%
Stress And Anxiety: 20 people, 20.20%
Fatigue (feeling of tiredness): 18 people, 18.18%
Malaise (a feeling of general discomfort or uneasiness): 17 people, 17.17%
Dizziness: 15 people, 15.15%
Pain: 14 people, 14.14%
Agitation (state of anxiety or nervous excitement): 14 people, 14.14%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 13 people, 13.13%
Hyperhidrosis (abnormally increased sweating): 12 people, 12.12%

What are the existing conditions these people have? *

Pain: 20 people, 20.20%
Fibromyalgia (a long-term condition which causes pain all over the body): 17 people, 17.17%
Depression: 15 people, 15.15%
Stress And Anxiety: 13 people, 13.13%
Muscle Spasms (muscle contraction): 13 people, 13.13%
Hypersensitivity: 13 people, 13.13%
Neuralgia (pain in one or more nerves): 12 people, 12.12%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 9 people, 9.09%
Constipation: 8 people, 8.08%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 8.08%

* Approximation only. Some reports may have incomplete information.

Do you take Biotin and have Withdrawal syndrome?

- Check whether Withdrawal syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Biotin:

Biotin (35,393 reports)

Browse all side effects of Biotin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Withdrawal syndrome:

Withdrawal syndrome (1,003 drugs)

Browse all the conditions that are associated with Withdrawal syndrome:

Withdrawal syndrome (1,484 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on biotin (the active ingredients of Biotin) and Biotin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.