Bisacodyl and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Bisacodyl (bisacodyl), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Pain.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Bisacodyl. It is created by eHealthMe based on reports of 18,779 people who have side effects when taking Bisacodyl from the FDA, and is updated regularly.

What is Bisacodyl?

Bisacodyl has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 18,852 Bisacodyl users. Check the latest studies of Bisacodyl.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,042 drugs and 1,782 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.



On Jul, 08, 2026

18,779 people reported to have side effects when taking Bisacodyl.
Among them, 44 people (0.23%) have Clostridium difficile colitis.

Could Bisacodyl cause Clostridium difficile colitis?

Among these 44 people:

How long have people been on Bisacodyl when they have Clostridium difficile colitis? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Clostridium difficile colitis when taking Bisacodyl? *

  • female: 59.52 %
  • male: 40.48 %

What is the age of people who have Clostridium difficile colitis when taking Bisacodyl? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 20 %
  • 50-59: 10 %
  • 60+: 70 %

What are other drugs people take besides Bisacodyl? *

  1. Acetaminophen: 22 people, 50.00%
  2. Lorazepam: 17 people, 38.64%
  3. Omeprazole: 14 people, 31.82%
  4. Colace: 14 people, 31.82%
  5. Aspirin: 13 people, 29.55%
  6. Tylenol: 12 people, 27.27%
  7. Ondansetron: 12 people, 27.27%
  8. Xanax: 12 people, 27.27%
  9. Ms Contin: 11 people, 25.00%
  10. Furosemide: 11 people, 25.00%

What are other side effects people have besides Clostridium difficile colitis? *

  1. Pneumonia: 21 people, 47.73%
  2. Urinary Tract Infection: 18 people, 40.91%
  3. Acute Kidney Failure: 16 people, 36.36%
  4. Weakness: 16 people, 36.36%
  5. Cardiac Failure Congestive: 16 people, 36.36%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 15 people, 34.09%
  7. Dyspnea (difficult or laboured breathing): 15 people, 34.09%
  8. Atelectasis (partial or complete collapse of the lung): 14 people, 31.82%
  9. Thrombocytopenia (decrease of platelets in blood): 14 people, 31.82%
  10. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 13 people, 29.55%

What are the existing conditions these people have? *

  1. Pain: 12 people, 27.27%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 18.18%
  3. Metastases To Bone (cancer spreads to bone): 5 people, 11.36%
  4. High Blood Pressure: 5 people, 11.36%
  5. Diarrhea: 4 people, 9.09%
  6. Headache (pain in head): 4 people, 9.09%
  7. Chest Pain: 3 people, 6.82%
  8. Stress And Anxiety: 3 people, 6.82%
  9. Joint Pain: 2 people, 4.55%
  10. Insomnia (sleeplessness): 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Bisacodyl and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bisacodyl:

Clostridium difficile colitis treatments and more:

How severe was Clostridium difficile colitis and when was it recovered:

Expand to all the drugs that have ingredients of bisacodyl:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bisacodyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Browse all the conditions that are associated with Clostridium difficile colitis:


How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl (the active ingredients of Bisacodyl) and Bisacodyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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