Boniva and Left ventricular hypertrophy - a phase IV clinical study of FDA data

Summary:

Left ventricular hypertrophy is reported as a side effect among people who take Boniva (ibandronate sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Fosamax, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Left ventricular hypertrophy when taking Boniva. It is created by eHealthMe based on reports of 26,949 people who have side effects when taking Boniva from the FDA, and is updated regularly.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

What is Left ventricular hypertrophy?

Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart) is found to be associated with 896 drugs and 756 conditions by eHealthMe. Check the latest studies of Left ventricular hypertrophy.

On Aug, 01, 2026

26,949 people reported to have side effects when taking Boniva.
Among them, 49 people (0.18%) have Left ventricular hypertrophy.

Could Boniva cause Left ventricular hypertrophy?

Among these 49 people:

How long have people been on Boniva when they have Left ventricular hypertrophy? *

What is the gender of people who have Left ventricular hypertrophy when taking Boniva? *

female: 73.33 %
male: 26.67 %

What is the age of people who have Left ventricular hypertrophy when taking Boniva? *

What are other drugs people take besides Boniva? *

What are other side effects people have besides Left ventricular hypertrophy? *

Femur Fracture: 31 people, 63.27%
Nausea (feeling of having an urge to vomit): 28 people, 57.14%
High Blood Pressure: 27 people, 55.10%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 27 people, 55.10%
Diarrhea: 25 people, 51.02%
Back Pain: 25 people, 51.02%
Weakness: 22 people, 44.90%
Weight Decreased: 19 people, 38.78%
Memory Loss: 18 people, 36.73%
Mitral Valve Incompetence (inefficient heart valve): 18 people, 36.73%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 17 people, 34.69%
Hypersensitivity: 5 people, 10.20%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.20%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.12%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 4.08%
Pain: 2 people, 4.08%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 2.04%
Arrhythmias (irregular heartbeat): 1 person, 2.04%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.04%
Bipolar Disorder (mood disorder): 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Boniva and have Left ventricular hypertrophy?

- Check whether Left ventricular hypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Boniva:

Boniva (27,340 reports)

Browse all side effects of Boniva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (896 drugs)

Browse all the conditions that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (756 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ibandronate sodium (the active ingredients of Boniva) and Boniva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.