Boniva and Wax blockage - a phase IV clinical study of FDA data

Summary:

Wax blockage is reported as a side effect among people who take Boniva (ibandronate sodium), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Fosamax, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Wax blockage when taking Boniva. It is created by eHealthMe based on reports of 26,949 people who have side effects when taking Boniva from the FDA, and is updated regularly.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

What is Wax blockage?

Wax blockage is found to be associated with 410 drugs and 972 conditions by eHealthMe. Check the latest studies of Wax blockage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

26,949 people reported to have side effects when taking Boniva.
Among them, 52 people (0.19%) have Wax blockage.

Among these 52 people:

How long have people been on Boniva when they have Wax blockage? *

What is the gender of people who have Wax blockage when taking Boniva? *

female: 100 %
male: 0.0 %

What is the age of people who have Wax blockage when taking Boniva? *

What are other drugs people take besides Boniva? *

What are other side effects people have besides Wax blockage? *

Tooth Disorder (tooth disease): 29 people, 55.77%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 25 people, 48.08%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 23 people, 44.23%
Femur Fracture: 22 people, 42.31%
Depression: 21 people, 40.38%
Fatigue (feeling of tiredness): 20 people, 38.46%
High Blood Pressure: 20 people, 38.46%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 19 people, 36.54%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 18 people, 34.62%
Osteonecrosis Of Jaw (death of bone of jaw): 18 people, 34.62%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 15.38%
High Blood Cholesterol: 8 people, 15.38%
High Blood Pressure: 7 people, 13.46%
Senile Osteoporosis (weak bones with ageing): 4 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.77%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 3.85%
Stress And Anxiety: 2 people, 3.85%
Hypersensitivity: 2 people, 3.85%
Depression: 1 person, 1.92%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 1.92%

* Approximation only. Some reports may have incomplete information.

Do you take Boniva and have Wax blockage?

- Check whether Wax blockage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Boniva:

Boniva (27,340 reports)

Wax blockage treatments and more:

Wax blockage (1,960 reports)

Browse all side effects of Boniva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wax blockage:

Wax blockage (410 drugs)

Browse all the conditions that are associated with Wax blockage:

Wax blockage (972 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ibandronate sodium (the active ingredients of Boniva) and Boniva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.