Botox and Bi-polar - a phase IV clinical study of FDA data

Summary:

Bi-polar is reported as a side effect among people who take Botox (botulinum toxin type a), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Magnesium, and have Cataplexy.

The phase IV clinical study analyzes which people have Bi-polar when taking Botox. It is created by eHealthMe based on reports of 69,984 people who have side effects when taking Botox from the FDA, and is updated regularly.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

What is Bi-polar?

Bi-polar is found to be associated with 887 drugs and 1,211 conditions by eHealthMe. Check the latest studies of Bi-polar.

On Jul, 18, 2026

69,984 people reported to have side effects when taking Botox.
Among them, 44 people (0.06%) have Bi-polar.

Among these 44 people:

How long have people been on Botox when they have Bi-polar? *

What is the gender of people who have Bi-polar when taking Botox? *

female: 93.02 %
male: 6.98 %

What is the age of people who have Bi-polar when taking Botox? *

What are other drugs people take besides Botox? *

What are other side effects people have besides Bi-polar? *

Weight Increased: 15 people, 34.09%
Endometrial Cancer: 12 people, 27.27%
Restless Leg Syndrome (a powerful urge to move your legs): 12 people, 27.27%
Dizziness: 7 people, 15.91%
Fatigue (feeling of tiredness): 5 people, 11.36%
Drug Ineffective: 5 people, 11.36%
Depression: 5 people, 11.36%
Drug Effect Decreased: 4 people, 9.09%
Urinary Tract Infection: 4 people, 9.09%
Suicidal Ideation: 4 people, 9.09%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 25.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 25.00%
Skin Wrinkling (wrinkle on skin): 8 people, 18.18%
Stress And Anxiety: 3 people, 6.82%
Depression: 3 people, 6.82%
Drowsiness: 3 people, 6.82%
High Blood Cholesterol: 3 people, 6.82%
Thyroid Diseases: 2 people, 4.55%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 4.55%
Cardiac Disorder: 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Botox and have Bi-polar?

- Check whether Bi-polar is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Botox:

Botox (70,513 reports)

Bi-polar treatments and more:

Bi-polar (109,428 reports)

Browse all side effects of Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bi-polar:

Bi-polar (887 drugs)

Browse all the conditions that are associated with Bi-polar:

Bi-polar (1,211 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on botulinum toxin type a (the active ingredients of Botox) and Botox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.