Botox and Cutis laxa - a phase IV clinical study of FDA data
Summary:
Cutis laxa is reported as a side effect among people who take Botox (botulinum toxin type a), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Topamax, and have Skin wrinkling.
The phase IV clinical study analyzes which people have Cutis laxa when taking Botox. It is created by eHealthMe based on reports of 69,984 people who have side effects when taking Botox from the FDA, and is updated regularly.
What is Botox?
Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.
What is Cutis laxa?
Cutis laxa (connective tissue disorder in which the skin lacks elasticity and hangs in loose folds) is found to be associated with 128 drugs and 175 conditions by eHealthMe. Check the latest studies of Cutis laxa.
69,984 people reported to have side effects when taking Botox.
Among them, 24 people (0.03%) have Cutis laxa.

Among these 24 people:
How long have people been on Botox when they have Cutis laxa? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Cutis laxa when taking Botox? *
- female: 91.67 %
- male: 8.33 %
What is the age of people who have Cutis laxa when taking Botox? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 6.67 %
- 40-49: 13.33 %
- 50-59: 26.67 %
- 60+: 53.33 %
What are other drugs people take besides Botox? *
- Armour Thyroid: 2 people, 8.33%
- Topamax: 2 people, 8.33%
- Lasix: 1 person, 4.17%
- Calcium: 1 person, 4.17%
- Cordyceps: 1 person, 4.17%
- Dilantin: 1 person, 4.17%
- Dysport: 1 person, 4.17%
- Effexor: 1 person, 4.17%
- Fish Oil: 1 person, 4.17%
- Flexeril: 1 person, 4.17%
What are other side effects people have besides Cutis laxa? *
- Eyelid Ptosis (falling of the upper or lower eyelid): 7 people, 29.17%
- Facial Paresis (weakness in facial muscle movement): 7 people, 29.17%
- Drug Ineffective: 5 people, 20.83%
- Visual Impairment: 2 people, 8.33%
- Swelling Face: 2 people, 8.33%
- Swallowing Difficulty: 2 people, 8.33%
- Dyspnea (difficult or laboured breathing): 2 people, 8.33%
- Mydriasis (a dilation of the pupil): 2 people, 8.33%
- Overdose: 2 people, 8.33%
- Haemorrhage (bleeding): 1 person, 4.17%
What are the existing conditions these people have? *
- Skin Wrinkling (wrinkle on skin): 17 people, 70.83%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.33%
- Dizziness: 2 people, 8.33%
- Pain: 1 person, 4.17%
- Osteoporosis (bones weak and more likely to break): 1 person, 4.17%
- Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 4.17%
- Jaw Disorder (jaw disease): 1 person, 4.17%
- Intervertebral Disc Protrusion (spinal disc protrusion): 1 person, 4.17%
- Hypersensitivity: 1 person, 4.17%
- High Blood Pressure: 1 person, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Botox and have Cutis laxa?
- Check whether Cutis laxa is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Botox:
- Botox (70,513 reports)
Cutis laxa treatments and more:
- Cutis laxa (416 reports)
How severe was Cutis laxa and when was it recovered:
Expand to all the drugs that have ingredients of botulinum toxin type a:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Botox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Cutis laxa:
- Cutis laxa (128 drugs)
Browse all the conditions that are associated with Cutis laxa:
- Cutis laxa (175 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on botulinum toxin type a (the active ingredients of Botox) and Botox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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