Botox and Heart attack - a phase IV clinical study of FDA data
Summary:
Heart attack is reported as a side effect among people who take Botox (botulinum toxin type a), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cymbalta, and have Immunodeficiency common variable.
The phase IV clinical study analyzes which people have Heart attack when taking Botox. It is created by eHealthMe based on reports of 69,984 people who have side effects when taking Botox from the FDA, and is updated regularly.
What is Botox?
Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.
What is Heart attack?
Heart attack is found to be associated with 2,470 drugs and 3,298 conditions by eHealthMe. Check the latest studies of Heart attack.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
69,984 people reported to have side effects when taking Botox.
Among them, 93 people (0.13%) have Heart attack.

Among these 93 people:
How long have people been on Botox when they have Heart attack? *
- < 1 month: 84.38 %
- 1 - 6 months: 6.25 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 3.12 %
- 5 - 10 years: 0.0 %
- 10+ years: 6.25 %
What is the gender of people who have Heart attack when taking Botox? *
- female: 79.78 %
- male: 20.22 %
What is the age of people who have Heart attack when taking Botox? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 12.96 %
- 40-49: 20.37 %
- 50-59: 24.07 %
- 60+: 42.59 %
What are other drugs people take besides Botox? *
- Cymbalta: 14 people, 15.05%
- Amlodipine: 12 people, 12.90%
- Effexor: 11 people, 11.83%
- Oxycodone: 10 people, 10.75%
- Dexilant: 10 people, 10.75%
- Aimovig: 9 people, 9.68%
- Premarin: 9 people, 9.68%
- Synthroid: 8 people, 8.60%
- Bactrim Ds: 8 people, 8.60%
- Gabapentin: 8 people, 8.60%
What are other side effects people have besides Heart attack? *
- Urinary Tract Infection: 16 people, 17.20%
- Headache (pain in head): 15 people, 16.13%
- Dizziness: 14 people, 15.05%
- Chest Pain: 13 people, 13.98%
- Fatigue (feeling of tiredness): 13 people, 13.98%
- Nausea (feeling of having an urge to vomit): 12 people, 12.90%
- Stress And Anxiety: 12 people, 12.90%
- Infection: 11 people, 11.83%
- Pneumonia: 11 people, 11.83%
- Memory Loss: 10 people, 10.75%
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 10 people, 10.75%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 9.68%
- Eyelid Twitch (spontaneous and uncontrolled spasms of the muscles): 7 people, 7.53%
- Stress And Anxiety: 6 people, 6.45%
- Headache (pain in head): 6 people, 6.45%
- High Blood Pressure: 5 people, 5.38%
- Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 5 people, 5.38%
- Pain: 5 people, 5.38%
- Skin Wrinkling (wrinkle on skin): 5 people, 5.38%
- High Blood Cholesterol: 5 people, 5.38%
* Approximation only. Some reports may have incomplete information.
Do you take Botox and have Heart attack?
- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Botox:
- Botox (70,513 reports)
Heart attack treatments and more:
- Heart attack (266,145 reports)
How severe was Heart attack and when was it recovered:
Expand to all the drugs that have ingredients of botulinum toxin type a:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Botox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Heart attack:
- Heart attack (2,470 drugs)
Browse all the conditions that are associated with Heart attack:
- Heart attack (3,298 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on botulinum toxin type a (the active ingredients of Botox) and Botox (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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