Brexpiprazole and Akathisia - a phase IV clinical study of FDA data

Summary:

Akathisia is reported as a side effect among people who take Brexpiprazole (brexpiprazole), especially for people who are male, 20-29 old, have been taking the drug for < 1 month also take Aripiprazole, and have Schizophrenia.

The phase IV clinical study analyzes which people have Akathisia when taking Brexpiprazole. It is created by eHealthMe based on reports of 1,162 people who have side effects when taking Brexpiprazole from the FDA, and is updated regularly.

What is Brexpiprazole?

Brexpiprazole has active ingredients of brexpiprazole. eHealthMe is studying from 1,164 Brexpiprazole users. Check the latest studies of Brexpiprazole.

What is Akathisia?

Akathisia (a movement disorder characterized by a feeling of inner restlessness) is found to be associated with 441 drugs and 822 conditions by eHealthMe. Check the latest studies of Akathisia.

On Jul, 05, 2026

1,162 people reported to have side effects when taking Brexpiprazole.
Among them, 60 people (5.16%) have Akathisia.

Among these 60 people:

How long have people been on Brexpiprazole when they have Akathisia? *

What is the gender of people who have Akathisia when taking Brexpiprazole? *

female: 31.58 %
male: 68.42 %

What is the age of people who have Akathisia when taking Brexpiprazole? *

What are other drugs people take besides Brexpiprazole? *

What are other side effects people have besides Akathisia? *

Agitation (state of anxiety or nervous excitement): 23 people, 38.33%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 22 people, 36.67%
Drug Ineffective: 21 people, 35.00%
Insomnia (sleeplessness): 17 people, 28.33%
Stress And Anxiety: 14 people, 23.33%
Sedation: 11 people, 18.33%
Tardive Dyskinesia (a disorder that involves involuntary movements): 10 people, 16.67%
Hallucination, Auditory (perceiving sounds without auditory stimulus): 10 people, 16.67%
Activation Syndrome (suicidal or homicidal stimulation or agitation): 10 people, 16.67%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 9 people, 15.00%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 34 people, 56.67%
Depression: 9 people, 15.00%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 8 people, 13.33%
Stress And Anxiety: 7 people, 11.67%
Insomnia (sleeplessness): 6 people, 10.00%
Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 4 people, 6.67%
Sleep Disorder: 3 people, 5.00%
Psychotic Disorder: 3 people, 5.00%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 5.00%
Mood Swings (an extreme or rapid change in mood): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Brexpiprazole and have Akathisia?

- Check whether Akathisia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brexpiprazole:

Brexpiprazole (1,164 reports)

Akathisia treatments and more:

Akathisia (15,139 reports)

Browse all side effects of Brexpiprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Akathisia:

Akathisia (441 drugs)

Browse all the conditions that are associated with Akathisia:

Akathisia (822 conditions)

Related publications that referenced our studies

Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on brexpiprazole (the active ingredients of Brexpiprazole) and Brexpiprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.