Brimonidine and Cholestasis - a phase IV clinical study of FDA data

Summary:

Cholestasis is reported as a side effect among people who take Brimonidine (brimonidine), especially for people who are female, 60+ old, also take Furosemide, and have Chest pain.

The phase IV clinical study analyzes which people have Cholestasis when taking Brimonidine. It is created by eHealthMe based on reports of 6,250 people who have side effects when taking Brimonidine from the FDA, and is updated regularly.

What is Brimonidine?

Brimonidine has active ingredients of brimonidine. It is often used in glaucoma. eHealthMe is studying from 6,276 Brimonidine users. Check the latest studies of Brimonidine.

What is Cholestasis?

Cholestasis (a condition where bile cannot flow from the liver to the duodenum) is found to be associated with 1,033 drugs and 1,809 conditions by eHealthMe. Check the latest studies of Cholestasis.



On Jul, 17, 2026

6,250 people reported to have side effects when taking Brimonidine.
Among them, 11 people (0.18%) have Cholestasis.

Could Brimonidine cause Cholestasis?

Among these 11 people:

What is the gender of people who have Cholestasis when taking Brimonidine? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Cholestasis when taking Brimonidine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Brimonidine? *

  1. Clopidogrel: 10 people, 90.91%
  2. Aspirin: 10 people, 90.91%
  3. Nitroglycerin: 10 people, 90.91%
  4. Mirtazapine: 10 people, 90.91%
  5. Furosemide: 10 people, 90.91%
  6. Iodine: 9 people, 81.82%
  7. Alendronic Acid: 9 people, 81.82%
  8. Fentanyl: 9 people, 81.82%
  9. Pantoprazole: 6 people, 54.55%
  10. Pantoprazole Sodium: 4 people, 36.36%

What are other side effects people have besides Cholestasis? *

  1. Hepatocellular Injury (liver injury): 11 people, 100.00%
  2. Weight Decreased: 10 people, 90.91%
  3. Urinary Tract Infection: 10 people, 90.91%
  4. Night Sweats (sweating in night): 10 people, 90.91%
  5. Hypotonia (low muscle tone): 10 people, 90.91%
  6. General Physical Health Deterioration (weak health status): 10 people, 90.91%
  7. Gait Disturbance: 10 people, 90.91%
  8. Feeling Cold: 10 people, 90.91%
  9. Dry Mouth: 10 people, 90.91%
  10. Dry Eyes (lack of adequate tears): 10 people, 90.91%

What are the existing conditions these people have? *

  1. Depression: 10 people, 90.91%
  2. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 10 people, 90.91%
  3. Chest Pain: 10 people, 90.91%
  4. Scoliosis (a medical condition in which a person's spine is curved from side to side): 9 people, 81.82%
  5. Oedema Peripheral (superficial swelling): 3 people, 27.27%
  6. Stress And Anxiety: 1 person, 9.09%
  7. Septic Shock (shock due to blood infection): 1 person, 9.09%
  8. Constipation: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Brimonidine and have Cholestasis?

- Check whether Cholestasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brimonidine:

Cholestasis treatments and more:

How severe was Cholestasis and when was it recovered:

Expand to all the drugs that have ingredients of brimonidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Brimonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cholestasis:

Browse all the conditions that are associated with Cholestasis:


How the study uses the data?

The study uses data from the FDA. It is based on brimonidine (the active ingredients of Brimonidine) and Brimonidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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