Brintellix and Drug dependence - a phase IV clinical study of FDA data

Summary:

Drug dependence is reported as a side effect among people who take Brintellix (vortioxetine hydrobromide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Sulfamethoxazole And Trimethoprim, and have Bladder disorder.

The phase IV clinical study analyzes which people have Drug dependence when taking Brintellix. It is created by eHealthMe based on reports of 6,619 people who have side effects when taking Brintellix from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,749 Brintellix users. Check the latest studies of Brintellix.

What is Drug dependence?

Drug dependence is found to be associated with 1,256 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Drug dependence.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

6,619 people reported to have side effects when taking Brintellix.
Among them, 17 people (0.26%) have Drug dependence.

Among these 17 people:

How long have people been on Brintellix when they have Drug dependence? *

What is the gender of people who have Drug dependence when taking Brintellix? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Drug dependence when taking Brintellix? *

What are other drugs people take besides Brintellix? *

Zyrtec: 4 people, 23.53%
Synthroid: 4 people, 23.53%
Lopressor: 4 people, 23.53%
Ditropan: 4 people, 23.53%
Zantac: 4 people, 23.53%
Reclast: 4 people, 23.53%
Restasis: 4 people, 23.53%
Rythmol: 4 people, 23.53%
Estrace: 4 people, 23.53%
Sulfamethoxazole And Trimethoprim: 4 people, 23.53%

What are other side effects people have besides Drug dependence? *

Stress And Anxiety: 7 people, 41.18%
Feeling Abnormal: 5 people, 29.41%
Drug Ineffective: 4 people, 23.53%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 3 people, 17.65%
Thinking Abnormal: 3 people, 17.65%
Memory Loss: 3 people, 17.65%
Sleep Disorder: 3 people, 17.65%
Dizziness: 3 people, 17.65%
Nervousness: 3 people, 17.65%
Disturbance In Attention: 2 people, 11.76%

What are the existing conditions these people have? *

Sleep Disorder: 4 people, 23.53%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 4 people, 23.53%
Infection: 4 people, 23.53%
Hypersensitivity: 4 people, 23.53%
Bladder Disorder: 4 people, 23.53%
Urinary Tract Infection: 3 people, 17.65%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 17.65%
Bone Disorder: 2 people, 11.76%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.88%
Asthma: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Brintellix and have Drug dependence?

- Check whether Drug dependence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brintellix:

Brintellix (6,749 reports)

Drug dependence treatments and more:

Drug dependence (203,373 reports)

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug dependence:

Drug dependence (1,256 drugs)

Browse all the conditions that are associated with Drug dependence:

Drug dependence (1,139 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Brintellix) and Brintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.