Brintellix and Sleep disorder - a phase IV clinical study of FDA data

Summary:

Sleep disorder is reported as a side effect among people who take Brintellix (vortioxetine hydrobromide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Vitamin B12, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Sleep disorder when taking Brintellix. It is created by eHealthMe based on reports of 6,619 people who have side effects when taking Brintellix from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Sleep disorder?

Sleep disorder is found to be associated with 2,103 drugs and 2,938 conditions by eHealthMe. Check the latest studies of Sleep disorder.

On Jul, 12, 2026

6,619 people reported to have side effects when taking Brintellix.
Among them, 40 people (0.6%) have Sleep disorder.

Among these 40 people:

How long have people been on Brintellix when they have Sleep disorder? *

What is the gender of people who have Sleep disorder when taking Brintellix? *

female: 56.76 %
male: 43.24 %

What is the age of people who have Sleep disorder when taking Brintellix? *

What are other drugs people take besides Brintellix? *

What are other side effects people have besides Sleep disorder? *

Nausea (feeling of having an urge to vomit): 9 people, 22.50%
Stress And Anxiety: 9 people, 22.50%
Anger: 8 people, 20.00%
Nervousness: 7 people, 17.50%
Headache (pain in head): 7 people, 17.50%
Drug Ineffective: 6 people, 15.00%
Weight Increased: 5 people, 12.50%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 5 people, 12.50%
Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 12.50%
Nausea And Vomiting: 4 people, 10.00%

What are the existing conditions these people have? *

Stress And Anxiety: 5 people, 12.50%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 10.00%
Parkinson's Disease: 3 people, 7.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.50%
High Blood Cholesterol: 2 people, 5.00%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 5.00%
Bipolar Disorder (mood disorder): 2 people, 5.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.00%
Nausea (feeling of having an urge to vomit): 2 people, 5.00%
Constipation: 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Brintellix and have Sleep disorder?

- Check whether Sleep disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brintellix:

Brintellix (6,748 reports)

Sleep disorder treatments and more:

Sleep disorder (167,338 reports)

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sleep disorder:

Sleep disorder (2,103 drugs)

Browse all the conditions that are associated with Sleep disorder:

Sleep disorder (2,938 conditions)

Related publications that referenced our studies

Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Brintellix) and Brintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.