Brintellix and Urticaria - a phase IV clinical study of FDA data

Summary:

Urticaria is reported as a side effect among people who take Brintellix (vortioxetine hydrobromide), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Synthroid, and have Major depression.

The phase IV clinical study analyzes which people have Urticaria when taking Brintellix. It is created by eHealthMe based on reports of 6,619 people who have side effects when taking Brintellix from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,749 Brintellix users. Check the latest studies of Brintellix.

What is Urticaria?

Urticaria (rash of round, red welts on the skin that itch intensely) is found to be associated with 2,613 drugs and 2,954 conditions by eHealthMe. Check the latest studies of Urticaria.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

6,619 people reported to have side effects when taking Brintellix.
Among them, 67 people (1.01%) have Urticaria.

Among these 67 people:

How long have people been on Brintellix when they have Urticaria? *

What is the gender of people who have Urticaria when taking Brintellix? *

female: 85.25 %
male: 14.75 %

What is the age of people who have Urticaria when taking Brintellix? *

What are other drugs people take besides Brintellix? *

What are other side effects people have besides Urticaria? *

Itching: 19 people, 28.36%
Rashes (redness): 9 people, 13.43%
Nausea (feeling of having an urge to vomit): 8 people, 11.94%
Dyspnea (difficult or laboured breathing): 6 people, 8.96%
Nausea And Vomiting: 5 people, 7.46%
Diarrhea: 4 people, 5.97%
Drug Ineffective: 4 people, 5.97%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 4 people, 5.97%
Swollen Tongue (swelling of tongue): 4 people, 5.97%
Eye Swelling: 3 people, 4.48%

What are the existing conditions these people have? *

Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 24 people, 35.82%
Stress And Anxiety: 8 people, 11.94%
Thyroid Diseases: 4 people, 5.97%
High Blood Cholesterol: 4 people, 5.97%
Asthma: 3 people, 4.48%
Pain: 3 people, 4.48%
Otitis Externa (external ear infection): 3 people, 4.48%
Type 2 Diabetes: 3 people, 4.48%
Insomnia (sleeplessness): 2 people, 2.99%
Weight Loss: 1 person, 1.49%

* Approximation only. Some reports may have incomplete information.

Do you take Brintellix and have Urticaria?

- Check whether Urticaria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brintellix:

Brintellix (6,749 reports)

Urticaria treatments and more:

Urticaria (173,777 reports)

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urticaria:

Urticaria (2,613 drugs)

Browse all the conditions that are associated with Urticaria:

Urticaria (2,954 conditions)

Related publications that referenced our studies

Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
Musri FY, Mutlu H, K?vrak Salim D, Karakurt Ery?lmaz M, ?nal B, Tural D, ?enol Co?kun H, "Sorafenib-induced severe urticaria in a patient with hepatocellular cancer", Journal of Oncology Pharmacy Practice, 2016 Jan .
Semira ZA, Zulfkar Q, Sameem F, "Livedo reticularis associated with dapsone therapy in a patient with chronic urticaria", Indian journal of pharmacology, 2014 Jan .
Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
Musri FY, Mutlu H, K?vrak Salim D, Karakurt Ery?lmaz M, ?nal B, Tural D, ?enol Co?kun H, "Sorafenib-induced severe urticaria in a patient with hepatocellular cancer", Journal of Oncology Pharmacy Practice, 2016 Jan .
Semira ZA, Zulfkar Q, Sameem F, "Livedo reticularis associated with dapsone therapy in a patient with chronic urticaria", Indian journal of pharmacology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Brintellix) and Brintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.