Bumex and Lactic acidosis - a phase IV clinical study of FDA data

Summary:

Lactic acidosis is reported as a side effect among people who take Bumex (bumetanide), especially for people who are female, 60+ old, also take Glucophage, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Lactic acidosis when taking Bumex. It is created by eHealthMe based on reports of 9,078 people who have side effects when taking Bumex from the FDA, and is updated regularly.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

What is Lactic acidosis?

Lactic acidosis (low ph in body tissues) is found to be associated with 995 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Lactic acidosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

9,078 people reported to have side effects when taking Bumex.
Among them, 23 people (0.25%) have Lactic acidosis.

Among these 23 people:

What is the gender of people who have Lactic acidosis when taking Bumex? *

female: 69.57 %
male: 30.43 %

What is the age of people who have Lactic acidosis when taking Bumex? *

What are other drugs people take besides Bumex? *

What are other side effects people have besides Lactic acidosis? *

Nausea (feeling of having an urge to vomit): 12 people, 52.17%
Hypotension (abnormally low blood pressure): 10 people, 43.48%
Acute Kidney Failure: 9 people, 39.13%
Dehydration (dryness resulting from the removal of water): 9 people, 39.13%
Diarrhea: 8 people, 34.78%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 8 people, 34.78%
Nausea And Vomiting: 8 people, 34.78%
Pneumonia: 7 people, 30.43%
International Normalised Ratio Increased: 7 people, 30.43%
Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 30.43%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 30.43%
Type 2 Diabetes: 5 people, 21.74%
Diabetes: 3 people, 13.04%
Hepatitis C: 2 people, 8.70%
Wernicke's Encephalopathy (ocular disturbances, changes in mental state, unsteady stance and gait due to deficiency of vit.b1): 1 person, 4.35%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.35%
Cardiac Failure Congestive: 1 person, 4.35%
Coronary Artery Aneurysm: 1 person, 4.35%
Encephalitis (inflammation of the brain): 1 person, 4.35%
Endocarditis (inflammation in heart muscle): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Bumex and have Lactic acidosis?

- Check whether Lactic acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bumex:

Bumex (9,210 reports)

Lactic acidosis treatments and more:

Lactic acidosis (34,314 reports)

Browse all side effects of Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lactic acidosis:

Lactic acidosis (995 drugs)

Browse all the conditions that are associated with Lactic acidosis:

Lactic acidosis (1,281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide (the active ingredients of Bumex) and Bumex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.