Bumex and Sleeping difficulty - a phase IV clinical study of FDA data

Summary:

Sleeping difficulty is reported as a side effect among people who take Bumex (bumetanide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coreg, and have Pain.

The phase IV clinical study analyzes which people have Sleeping difficulty when taking Bumex. It is created by eHealthMe based on reports of 9,078 people who have side effects when taking Bumex from the FDA, and is updated regularly.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

What is Sleeping difficulty?

Sleeping difficulty (difficult sleeping) is found to be associated with 4,252 drugs and 5,348 conditions by eHealthMe. Check the latest studies of Sleeping difficulty.

On Oct, 18, 2025

9,078 people reported to have side effects when taking Bumex.
Among them, 177 people (1.95%) have Sleeping difficulty.

Among these 177 people:

How long have people been on Bumex when they have Sleeping difficulty? *

What is the gender of people who have Sleeping difficulty when taking Bumex? *

female: 54.17 %
male: 45.83 %

What is the age of people who have Sleeping difficulty when taking Bumex? *

What are other drugs people take besides Bumex? *

What are other side effects people have besides Sleeping difficulty? *

Nausea (feeling of having an urge to vomit): 72 people, 40.68%
Pain: 65 people, 36.72%
Weakness: 62 people, 35.03%
Fatigue (feeling of tiredness): 61 people, 34.46%
Dyspnea (difficult or laboured breathing): 59 people, 33.33%
Stress And Anxiety: 48 people, 27.12%
Constipation: 47 people, 26.55%
Cardiac Failure Congestive: 43 people, 24.29%
Dizziness: 42 people, 23.73%
Oedema Peripheral (superficial swelling): 41 people, 23.16%

What are the existing conditions these people have? *

Pain: 29 people, 16.38%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 23 people, 12.99%
High Blood Pressure: 11 people, 6.21%
Multiple Myeloma (cancer of the plasma cells): 11 people, 6.21%
High Blood Cholesterol: 11 people, 6.21%
Depression: 9 people, 5.08%
Prostate Cancer: 9 people, 5.08%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 5.08%
Diabetes: 8 people, 4.52%
Oedema (fluid collection in tissue): 8 people, 4.52%

* Approximation only. Some reports may have incomplete information.

Do you take Bumex and have Sleeping difficulty?

- Check whether Sleeping difficulty is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bumex:

Bumex (9,210 reports)

Browse all side effects of Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sleeping difficulty:

Browse all the drugs that are associated with Sleeping difficulty:

Sleeping difficulty (4,252 drugs)

Common conditions associated with Sleeping difficulty:

Depression aggravated: 17,540 reports
Antidepressant therapy: 17,500 reports
Pain: 13,668 reports
Rheumatoid arthritis aggravated: 13,625 reports
Pain relief: 13,485 reports
Multiple sclerosis: 12,998 reports
Hypertension aggravated: 12,107 reports
Blood pressure increased: 12,061 reports
Anxiety aggravated: 10,450 reports
Anxiety: 10,449 reports

Browse all the conditions that are associated with Sleeping difficulty:

Sleeping difficulty (5,348 conditions)

Drugs similar to Bumex and Sleeping difficulty :

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide (the active ingredients of Bumex) and Bumex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.