Buspar and Hiatal hernia - a phase IV clinical study of FDA data

Summary:

Hiatal hernia is reported as a side effect among people who take Buspar (buspirone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Fosamax, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Hiatal hernia when taking Buspar. It is created by eHealthMe based on reports of 17,598 people who have side effects when taking Buspar from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Hiatal hernia?

Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm) is found to be associated with 1,305 drugs and 1,564 conditions by eHealthMe. Check the latest studies of Hiatal hernia.



On Jul, 04, 2026

17,598 people reported to have side effects when taking Buspar.
Among them, 68 people (0.39%) have Hiatal hernia.

Could Buspar cause Hiatal hernia?

Among these 68 people:

How long have people been on Buspar when they have Hiatal hernia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hiatal hernia when taking Buspar? *

  • female: 68.66 %
  • male: 31.34 %

What is the age of people who have Hiatal hernia when taking Buspar? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.64 %
  • 30-39: 3.28 %
  • 40-49: 6.56 %
  • 50-59: 19.67 %
  • 60+: 68.85 %

What are other drugs people take besides Buspar? *

  1. Fosamax: 25 people, 36.76%
  2. Synthroid: 21 people, 30.88%
  3. Oxycontin: 20 people, 29.41%
  4. Colace: 20 people, 29.41%
  5. Vioxx: 20 people, 29.41%
  6. Celebrex: 19 people, 27.94%
  7. Zantac: 19 people, 27.94%
  8. Lortab: 19 people, 27.94%
  9. Cimetidine: 19 people, 27.94%
  10. Zofran: 19 people, 27.94%

What are other side effects people have besides Hiatal hernia? *

  1. Constipation: 28 people, 41.18%
  2. Nausea And Vomiting: 27 people, 39.71%
  3. High Blood Cholesterol: 27 people, 39.71%
  4. Hypercalcaemia (elevated calcium (ca+) level in the blood): 26 people, 38.24%
  5. Dyspnea (difficult or laboured breathing): 25 people, 36.76%
  6. Gastric Ulcer (stomach ulcer): 25 people, 36.76%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 23 people, 33.82%
  8. Nausea (feeling of having an urge to vomit): 23 people, 33.82%
  9. Spinal Osteoarthritis (joint cartilage loss in spine): 23 people, 33.82%
  10. Osteoporosis (bones weak and more likely to break): 22 people, 32.35%

What are the existing conditions these people have? *

  1. Ovarian Cancer (cancer of ovary): 9 people, 13.24%
  2. Insomnia (sleeplessness): 7 people, 10.29%
  3. High Blood Pressure: 6 people, 8.82%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.82%
  5. Nausea (feeling of having an urge to vomit): 6 people, 8.82%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 7.35%
  7. Growth Hormone Deficiency: 4 people, 5.88%
  8. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 4 people, 5.88%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 5.88%
  10. Fatigue (feeling of tiredness): 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Buspar and have Hiatal hernia?

- Check whether Hiatal hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buspar:

Hiatal hernia treatments and more:

How severe was Hiatal hernia and when was it recovered:

Expand to all the drugs that have ingredients of buspirone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hiatal hernia:

Browse all the conditions that are associated with Hiatal hernia:


How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride (the active ingredients of Buspar) and Buspar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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