Buspar and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Buspar (buspirone hydrochloride), especially for people who are female, 50-59 old, also take Paxil, and have Pain.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Buspar. It is created by eHealthMe based on reports of 17,598 people who have side effects when taking Buspar from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,462 Buspar users. Check the latest studies of Buspar.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,957 drugs and 2,937 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

On May, 02, 2026

17,598 people reported to have side effects when taking Buspar.
Among them, 64 people (0.36%) have Hyperkalemia.

Among these 64 people:

What is the gender of people who have Hyperkalemia when taking Buspar? *

female: 68.75 %
male: 31.25 %

What is the age of people who have Hyperkalemia when taking Buspar? *

What are other drugs people take besides Buspar? *

What are other side effects people have besides Hyperkalemia? *

Acute Kidney Failure: 16 people, 25.00%
High Blood Pressure: 14 people, 21.88%
Hypotension (abnormally low blood pressure): 12 people, 18.75%
Fatigue (feeling of tiredness): 11 people, 17.19%
Insomnia (sleeplessness): 9 people, 14.06%
Weakness: 9 people, 14.06%
International Normalised Ratio Increased: 9 people, 14.06%
Chest Pain: 9 people, 14.06%
Headache (pain in head): 8 people, 12.50%
Pain: 8 people, 12.50%

What are the existing conditions these people have? *

Pain: 7 people, 10.94%
Cardiac Disorder: 5 people, 7.81%
High Blood Pressure: 4 people, 6.25%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 6.25%
Indigestion: 3 people, 4.69%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 4.69%
Liver Disorder (liver diseases): 3 people, 4.69%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 4.69%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 4.69%
Insomnia (sleeplessness): 2 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Buspar and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buspar:

Buspar (20,462 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,084 reports)

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,957 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,937 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride (the active ingredients of Buspar) and Buspar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.