Buspar and Hypomania - a phase IV clinical study of FDA data

Summary:

Hypomania is reported as a side effect among people who take Buspar (buspirone hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Seroquel, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Hypomania when taking Buspar. It is created by eHealthMe based on reports of 17,598 people who have side effects when taking Buspar from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,463 Buspar users. Check the latest studies of Buspar.

What is Hypomania?

Hypomania (a mild form of mania, marked by elation and hyperactivity) is found to be associated with 365 drugs and 520 conditions by eHealthMe. Check the latest studies of Hypomania.

On Aug, 04, 2026

17,598 people reported to have side effects when taking Buspar.
Among them, 15 people (0.09%) have Hypomania.

Among these 15 people:

How long have people been on Buspar when they have Hypomania? *

What is the gender of people who have Hypomania when taking Buspar? *

female: 73.33 %
male: 26.67 %

What is the age of people who have Hypomania when taking Buspar? *

What are other drugs people take besides Buspar? *

What are other side effects people have besides Hypomania? *

Suicidal Ideation: 7 people, 46.67%
Insomnia (sleeplessness): 5 people, 33.33%
Agitation (state of anxiety or nervous excitement): 5 people, 33.33%
Fatigue (feeling of tiredness): 4 people, 26.67%
Joint Pain: 4 people, 26.67%
Bipolar Disorder (mood disorder): 4 people, 26.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 20.00%
Confusional State: 3 people, 20.00%
Disturbance In Attention: 3 people, 20.00%
Chest Pain: 3 people, 20.00%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 5 people, 33.33%
Migraine (headache): 3 people, 20.00%
Insomnia (sleeplessness): 3 people, 20.00%
Pain: 3 people, 20.00%
Sleep Disorder: 2 people, 13.33%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 13.33%
Constipation: 2 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 13.33%
Quit Smoking: 2 people, 13.33%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Buspar and have Hypomania?

- Check whether Hypomania is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buspar:

Buspar (20,463 reports)

Hypomania treatments and more:

Hypomania (4,914 reports)

Browse all side effects of Buspar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypomania:

Hypomania (365 drugs)

Browse all the conditions that are associated with Hypomania:

Hypomania (520 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buspirone hydrochloride (the active ingredients of Buspar) and Buspar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.