Busulfan and Haemolysis - a phase IV clinical study of FDA data

Summary:

Haemolysis is reported as a side effect among people who take Busulfan (busulfan), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Treanda, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Haemolysis when taking Busulfan. It is created by eHealthMe based on reports of 14,527 people who have side effects when taking Busulfan from the FDA, and is updated regularly.

What is Busulfan?

Busulfan has active ingredients of busulfan. eHealthMe is studying from 14,527 Busulfan users. Check the latest studies of Busulfan.

What is Haemolysis?

Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid) is found to be associated with 611 drugs and 837 conditions by eHealthMe. Check the latest studies of Haemolysis.



On Jul, 26, 2026

14,527 people reported to have side effects when taking Busulfan.
Among them, 48 people (0.33%) have Haemolysis.

Could Busulfan cause Haemolysis?

Among these 48 people:

How long have people been on Busulfan when they have Haemolysis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Haemolysis when taking Busulfan? *

  • female: 31.82 %
  • male: 68.18 %

What is the age of people who have Haemolysis when taking Busulfan? *

  • 0-1: 4.76 %
  • 2-9: 4.76 %
  • 10-19: 9.52 %
  • 20-29: 4.76 %
  • 30-39: 7.14 %
  • 40-49: 0.0 %
  • 50-59: 9.52 %
  • 60+: 59.52 %

What are other drugs people take besides Busulfan? *

  1. Treanda: 18 people, 37.50%
  2. Rituxan: 14 people, 29.17%
  3. Methotrexate: 11 people, 22.92%
  4. Diflucan: 10 people, 20.83%
  5. Aloxi: 9 people, 18.75%
  6. Amikin: 9 people, 18.75%
  7. Heparin: 8 people, 16.67%
  8. Valtrex: 8 people, 16.67%
  9. Emend: 7 people, 14.58%
  10. Duspatalin: 7 people, 14.58%

What are other side effects people have besides Haemolysis? *

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 20 people, 41.67%
  2. Febrile Neutropenia (fever with reduced white blood cells): 20 people, 41.67%
  3. Bacteraemia (presence of bacteria in the blood): 19 people, 39.58%
  4. Neuropathy Peripheral (surface nerve damage): 19 people, 39.58%
  5. Blood Count Abnormal: 18 people, 37.50%
  6. Neoplasm Progression (growth of tumour): 17 people, 35.42%
  7. Blood Bilirubin Increased: 9 people, 18.75%
  8. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 8 people, 16.67%
  9. Hepatic Enzyme Increased: 8 people, 16.67%
  10. Death: 8 people, 16.67%

What are the existing conditions these people have? *

  1. Bone Marrow Conditioning Regimen: 23 people, 47.92%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 19 people, 39.58%
  3. Gout (uric acid crystals building up in the body): 9 people, 18.75%
  4. Bacterial Infection: 9 people, 18.75%
  5. Nausea (feeling of having an urge to vomit): 8 people, 16.67%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 16.67%
  7. Essential Hypertension (primary hypertension): 8 people, 16.67%
  8. Nausea And Vomiting: 6 people, 12.50%
  9. Urination - Excessive Volume: 1 person, 2.08%
  10. Blast Crisis In Myelogenous Leukaemia: 1 person, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Busulfan and have Haemolysis?

- Check whether Haemolysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Busulfan:

Haemolysis treatments and more:

How severe was Haemolysis and when was it recovered:

Expand to all the drugs that have ingredients of busulfan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Busulfan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemolysis:

Browse all the conditions that are associated with Haemolysis:


How the study uses the data?

The study uses data from the FDA. It is based on busulfan (the active ingredients of Busulfan) and Busulfan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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