Busulfan and Hyperammonaemia - a phase IV clinical study of FDA data

Summary:

Hyperammonaemia is reported as a side effect among people who take Busulfan (busulfan), especially for people who are male, 20-29 old, also take Vancomycin, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Hyperammonaemia when taking Busulfan. It is created by eHealthMe based on reports of 14,527 people who have side effects when taking Busulfan from the FDA, and is updated regularly.

What is Busulfan?

Busulfan has active ingredients of busulfan. eHealthMe is studying from 14,527 Busulfan users. Check the latest studies of Busulfan.

What is Hyperammonaemia?

Hyperammonaemia is found to be associated with 397 drugs and 562 conditions by eHealthMe. Check the latest studies of Hyperammonaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

14,527 people reported to have side effects when taking Busulfan.
Among them, 21 people (0.14%) have Hyperammonaemia.

Among these 21 people:

What is the gender of people who have Hyperammonaemia when taking Busulfan? *

female: 10.53 %
male: 89.47 %

What is the age of people who have Hyperammonaemia when taking Busulfan? *

What are other drugs people take besides Busulfan? *

What are other side effects people have besides Hyperammonaemia? *

Respiratory Alkalosis (elevated blood ph due to excess breathing): 9 people, 42.86%
Hyperventilation: 7 people, 33.33%
Bleeding Disorders: 6 people, 28.57%
Blood Bilirubin Increased: 6 people, 28.57%
Hyperammonaemic Encephalopathy (excess of ammonia in the blood, disorder or disease of the brain): 5 people, 23.81%
Ureaplasma Infection: 5 people, 23.81%
Brain Stem Syndrome: 5 people, 23.81%
Unresponsive To Stimuli: 4 people, 19.05%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 3 people, 14.29%
Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 14.29%

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 7 people, 33.33%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 23.81%
The Flu (the flu is caused by an influenza virus): 5 people, 23.81%
Juvenile Chronic Myelomonocytic Leukaemia (long lasting cancer of blood in childrens): 4 people, 19.05%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 14.29%
Pneumonia: 3 people, 14.29%
High Blood Pressure: 2 people, 9.52%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 9.52%
Pneumonia Cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 2 people, 9.52%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Busulfan and have Hyperammonaemia?

- Check whether Hyperammonaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Busulfan:

Busulfan (14,527 reports)

Hyperammonaemia treatments and more:

Hyperammonaemia (6,053 reports)

Browse all side effects of Busulfan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperammonaemia:

Hyperammonaemia (397 drugs)

Browse all the conditions that are associated with Hyperammonaemia:

Hyperammonaemia (562 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on busulfan (the active ingredients of Busulfan) and Busulfan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.