Busulfan and Lymphoma - a phase IV clinical study of FDA data
Summary:
Lymphoma is reported as a side effect among people who take Busulfan (busulfan), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Bone marrow conditioning regimen.
The phase IV clinical study analyzes which people have Lymphoma when taking Busulfan. It is created by eHealthMe based on reports of 14,527 people who have side effects when taking Busulfan from the FDA, and is updated regularly.
What is Busulfan?
Busulfan has active ingredients of busulfan. eHealthMe is studying from 14,527 Busulfan users. Check the latest studies of Busulfan.
What is Lymphoma?
Lymphoma (cancer that begins in immune system cells) is found to be associated with 958 drugs and 1,013 conditions by eHealthMe. Check the latest studies of Lymphoma.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
14,527 people reported to have side effects when taking Busulfan.
Among them, 29 people (0.2%) have Lymphoma.

Among these 29 people:
How long have people been on Busulfan when they have Lymphoma? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Lymphoma when taking Busulfan? *
- female: 25.93 %
- male: 74.07 %
What is the age of people who have Lymphoma when taking Busulfan? *
- 0-1: 0.0 %
- 2-9: 4 %
- 10-19: 8 %
- 20-29: 20 %
- 30-39: 16 %
- 40-49: 24 %
- 50-59: 12 %
- 60+: 16 %
What are other drugs people take besides Busulfan? *
- Cyclophosphamide: 14 people, 48.28%
- Cyclosporine: 9 people, 31.03%
- Methotrexate: 7 people, 24.14%
- Mycophenolate Mofetil: 6 people, 20.69%
- Fludarabine Phosphate: 5 people, 17.24%
- Fluconazole: 5 people, 17.24%
- Acyclovir: 4 people, 13.79%
- Revlimid: 4 people, 13.79%
- Melphalan: 4 people, 13.79%
- Thiotepa: 4 people, 13.79%
What are other side effects people have besides Lymphoma? *
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 9 people, 31.03%
- Pneumonia: 9 people, 31.03%
- Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 8 people, 27.59%
- Thrombocytopenia (decrease of platelets in blood): 7 people, 24.14%
- Fever: 6 people, 20.69%
- Nausea And Vomiting: 5 people, 17.24%
- Pain: 5 people, 17.24%
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 5 people, 17.24%
- Sinusitis (inflammation of sinus): 5 people, 17.24%
- Herpes Zoster: 4 people, 13.79%
What are the existing conditions these people have? *
- Bone Marrow Conditioning Regimen: 4 people, 13.79%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 10.34%
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 10.34%
- Transplant Rejection (a transplant material is not worked): 2 people, 6.90%
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 6.90%
- Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 6.90%
- Venoocclusive Liver Disease (small veins in the liver are obstructed): 1 person, 3.45%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 3.45%
- Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 1 person, 3.45%
- Immunodeficiency Disorders: 1 person, 3.45%
* Approximation only. Some reports may have incomplete information.
Do you take Busulfan and have Lymphoma?
- Check whether Lymphoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Busulfan:
- Busulfan (14,527 reports)
Lymphoma treatments and more:
- Lymphoma (33,395 reports)
How severe was Lymphoma and when was it recovered:
Expand to all the drugs that have ingredients of busulfan:
- Lymphoma and drugs with ingredients of busulfan (34 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Busulfan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Lymphoma:
- Lymphoma (958 drugs)
Browse all the conditions that are associated with Lymphoma:
- Lymphoma (1,013 conditions)
Related publications that referenced our studies
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
How the study uses the data?
The study uses data from the FDA. It is based on busulfan (the active ingredients of Busulfan) and Busulfan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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