Busulfan and Mental status changes - a phase IV clinical study of FDA data

Summary:

Mental status changes is reported as a side effect among people who take Busulfan (busulfan), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ciclosporin, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Mental status changes when taking Busulfan. It is created by eHealthMe based on reports of 14,527 people who have side effects when taking Busulfan from the FDA, and is updated regularly.

What is Busulfan?

Busulfan has active ingredients of busulfan. eHealthMe is studying from 14,527 Busulfan users. Check the latest studies of Busulfan.

What is Mental status changes?

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) is found to be associated with 1,497 drugs and 1,759 conditions by eHealthMe. Check the latest studies of Mental status changes.

On Jul, 24, 2026

14,527 people reported to have side effects when taking Busulfan.
Among them, 70 people (0.48%) have Mental status changes.

Could Busulfan cause Mental status changes?

Among these 70 people:

How long have people been on Busulfan when they have Mental status changes? *

What is the gender of people who have Mental status changes when taking Busulfan? *

female: 25.4 %
male: 74.6 %

What is the age of people who have Mental status changes when taking Busulfan? *

What are other drugs people take besides Busulfan? *

What are other side effects people have besides Mental status changes? *

Acute Kidney Failure: 19 people, 27.14%
Posterior Reversible Encephalopathy Syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss): 18 people, 25.71%
Headache (pain in head): 17 people, 24.29%
High Blood Pressure: 16 people, 22.86%
Fever: 15 people, 21.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 17.14%
Hypotension (abnormally low blood pressure): 11 people, 15.71%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 11 people, 15.71%
Anaemia (lack of blood): 11 people, 15.71%
Multi-Organ Failure (multisystem organ failure): 11 people, 15.71%

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 24 people, 34.29%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 10.00%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 7 people, 10.00%
Lymphoma (cancer that begins in immune system cells): 6 people, 8.57%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 4.29%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 3 people, 4.29%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 2 people, 2.86%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 2 people, 2.86%
Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 2.86%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Busulfan and have Mental status changes?

- Check whether Mental status changes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Busulfan:

Busulfan (14,527 reports)

Browse all side effects of Busulfan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental status changes:

Mental status changes (1,497 drugs)

Browse all the conditions that are associated with Mental status changes:

Mental status changes (1,759 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on busulfan (the active ingredients of Busulfan) and Busulfan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.