Butrans and Dysstasia - a phase IV clinical study of FDA data

Summary:

Dysstasia is reported as a side effect among people who take Butrans (buprenorphine), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Zopiclone, and have Osteoarthritis.

The phase IV clinical study analyzes which people have Dysstasia when taking Butrans. It is created by eHealthMe based on reports of 63,939 people who have side effects when taking Butrans from the FDA, and is updated regularly.

What is Butrans?

Butrans has active ingredients of buprenorphine. It is often used in pain. eHealthMe is studying from 64,148 Butrans users. Check the latest studies of Butrans.

What is Dysstasia?

Dysstasia (difficulty in standing) is found to be associated with 1,389 drugs and 1,368 conditions by eHealthMe. Check the latest studies of Dysstasia.

On Jul, 11, 2026

63,939 people reported to have side effects when taking Butrans.
Among them, 30 people (0.05%) have Dysstasia.

Among these 30 people:

How long have people been on Butrans when they have Dysstasia? *

What is the gender of people who have Dysstasia when taking Butrans? *

female: 42.31 %
male: 57.69 %

What is the age of people who have Dysstasia when taking Butrans? *

What are other drugs people take besides Butrans? *

Zopiclone: 7 people, 23.33%
Hydroxyzine: 5 people, 16.67%
Dilaudid: 4 people, 13.33%
Metformin: 4 people, 13.33%
Suboxone: 4 people, 13.33%
Subutex: 4 people, 13.33%
Symbicort: 4 people, 13.33%
Lyrica: 3 people, 10.00%
Zubsolv: 3 people, 10.00%
Hydrocodone Bitartrate And Acetaminophen: 3 people, 10.00%

What are other side effects people have besides Dysstasia? *

Weakness: 9 people, 30.00%
Joint Swelling: 6 people, 20.00%
Gait Disturbance: 6 people, 20.00%
Nausea And Vomiting: 6 people, 20.00%
Joint Pain: 6 people, 20.00%
Mental Impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 5 people, 16.67%
Dizziness: 5 people, 16.67%
Chest Pain: 5 people, 16.67%
Depression: 5 people, 16.67%
Hearing Impaired: 4 people, 13.33%

What are the existing conditions these people have? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 16.67%
Depression: 3 people, 10.00%
Cushing's Syndrome (obesity, a rounded face, increased fat): 3 people, 10.00%
Type 2 Diabetes: 2 people, 6.67%
Back Injury: 2 people, 6.67%
High Blood Cholesterol: 2 people, 6.67%
Back Pain: 2 people, 6.67%
Joint Pain: 2 people, 6.67%
Neck Injury: 2 people, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Butrans and have Dysstasia?

- Check whether Dysstasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Butrans:

Butrans (64,148 reports)

Dysstasia treatments and more:

Dysstasia (35,077 reports)

Browse all side effects of Butrans:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dysstasia:

Dysstasia (1,389 drugs)

Browse all the conditions that are associated with Dysstasia:

Dysstasia (1,368 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine (the active ingredients of Butrans) and Butrans (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.