Butrans and Facet joint syndrome - a phase IV clinical study of FDA data

Summary:

Facet joint syndrome is reported as a side effect among people who take Butrans (buprenorphine), especially for people who are female, 40-49 old, also take Prednisone, and have Migraine.

The phase IV clinical study analyzes which people have Facet joint syndrome when taking Butrans. It is created by eHealthMe based on reports of 63,939 people who have side effects when taking Butrans from the FDA, and is updated regularly.

What is Butrans?

Butrans has active ingredients of buprenorphine. It is often used in pain. eHealthMe is studying from 64,148 Butrans users. Check the latest studies of Butrans.

What is Facet joint syndrome?

Facet joint syndrome (problem with movement of the facet joints of the spine) is found to be associated with 466 drugs and 119 conditions by eHealthMe. Check the latest studies of Facet joint syndrome.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

63,939 people reported to have side effects when taking Butrans.
Among them, 84 people (0.13%) have Facet joint syndrome.

Could Butrans cause Facet joint syndrome?

Among these 84 people:

What is the gender of people who have Facet joint syndrome when taking Butrans? *

female: 100 %
male: 0.0 %

What is the age of people who have Facet joint syndrome when taking Butrans? *

What are other drugs people take besides Butrans? *

What are other side effects people have besides Facet joint syndrome? *

Dizziness: 84 people, 100.00%
Breast Cancer Stage Iii: 84 people, 100.00%
Depression: 84 people, 100.00%
Weakness: 84 people, 100.00%
High Blood Cholesterol: 84 people, 100.00%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 83 people, 98.81%
Duodenal Ulcer Perforation (untreated ulcer can burn through the wall of the stomach): 83 people, 98.81%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 83 people, 98.81%
Eyelid Twitch (spontaneous and uncontrolled spasms of the muscles): 83 people, 98.81%
Diarrhea: 83 people, 98.81%

What are the existing conditions these people have? *

Migraine (headache): 84 people, 100.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 81 people, 96.43%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 78 people, 92.86%
Psoriasis (immune-mediated disease that affects the skin): 58 people, 69.05%
Stress And Anxiety: 6 people, 7.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 7.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 2.38%
Indigestion: 1 person, 1.19%
Headache (pain in head): 1 person, 1.19%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 1.19%

* Approximation only. Some reports may have incomplete information.

Do you take Butrans and have Facet joint syndrome?

- Check whether Facet joint syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Butrans:

Butrans (64,148 reports)

Browse all side effects of Butrans:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Facet joint syndrome:

Facet joint syndrome (466 drugs)

Browse all the conditions that are associated with Facet joint syndrome:

Facet joint syndrome (119 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine (the active ingredients of Butrans) and Butrans (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.