Butrans and Hip joint replacement - a phase IV clinical study of FDA data

Summary:

Hip joint replacement is reported as a side effect among people who take Butrans (buprenorphine), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Fosamax, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hip joint replacement when taking Butrans. It is created by eHealthMe based on reports of 63,939 people who have side effects when taking Butrans from the FDA, and is updated regularly.

What is Butrans?

Butrans has active ingredients of buprenorphine. It is often used in pain. eHealthMe is studying from 64,148 Butrans users. Check the latest studies of Butrans.

What is Hip joint replacement?

Hip joint replacement is found to be associated with 857 drugs and 1,062 conditions by eHealthMe. Check the latest studies of Hip joint replacement.

On Aug, 11, 2026

63,939 people reported to have side effects when taking Butrans.
Among them, 38 people (0.06%) have Hip joint replacement.

Could Butrans cause Hip joint replacement?

Among these 38 people:

How long have people been on Butrans when they have Hip joint replacement? *

What is the gender of people who have Hip joint replacement when taking Butrans? *

female: 75 %
male: 25 %

What is the age of people who have Hip joint replacement when taking Butrans? *

What are other drugs people take besides Butrans? *

Enbrel: 16 people, 42.11%
Fosamax: 16 people, 42.11%
Folic Acid: 15 people, 39.47%
Cetirizine Hydrochloride: 14 people, 36.84%
Simponi: 14 people, 36.84%
Desoximetasone: 14 people, 36.84%
Prednisone: 14 people, 36.84%
Cimzia: 14 people, 36.84%
Arava: 14 people, 36.84%
Humira: 14 people, 36.84%

What are other side effects people have besides Hip joint replacement? *

Depression: 16 people, 42.11%
Joint Pain: 15 people, 39.47%
Abdominal Discomfort: 14 people, 36.84%
Fatigue (feeling of tiredness): 14 people, 36.84%
Infusion Related Reaction: 14 people, 36.84%
High Blood Pressure: 14 people, 36.84%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 14 people, 36.84%
Hand Deformity: 14 people, 36.84%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 36.84%
Hair Loss: 14 people, 36.84%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 39.47%
Migraine (headache): 14 people, 36.84%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 21.05%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 15.79%
Parkinson's Disease: 3 people, 7.89%
Synovitis (inflammation of the synovial membrane): 2 people, 5.26%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 5.26%
Hiv Infection: 2 people, 5.26%
Joint Pain: 2 people, 5.26%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Butrans and have Hip joint replacement?

- Check whether Hip joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Butrans:

Butrans (64,148 reports)

Browse all side effects of Butrans:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hip joint replacement:

Hip joint replacement (857 drugs)

Browse all the conditions that are associated with Hip joint replacement:

Hip joint replacement (1,062 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine (the active ingredients of Butrans) and Butrans (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.