Bydureon and Rotator cuff syndrome - a phase IV clinical study of FDA data

Summary:

Rotator cuff syndrome is reported as a side effect among people who take Bydureon (exenatide synthetic), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Metformin, and have Blood pressure abnormal.

The phase IV clinical study analyzes which people have Rotator cuff syndrome when taking Bydureon. It is created by eHealthMe based on reports of 24,229 people who have side effects when taking Bydureon from the FDA, and is updated regularly.

What is Bydureon?

Bydureon has active ingredients of exenatide synthetic. It is often used in type 2 diabetes. eHealthMe is studying from 24,309 Bydureon users. Check the latest studies of Bydureon.

What is Rotator cuff syndrome?

Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder) is found to be associated with 1,089 drugs and 1,120 conditions by eHealthMe. Check the latest studies of Rotator cuff syndrome.



On Jul, 07, 2026

24,229 people reported to have side effects when taking Bydureon.
Among them, 17 people (0.07%) have Rotator cuff syndrome.

Could Bydureon cause Rotator cuff syndrome?

Among these 17 people:

How long have people been on Bydureon when they have Rotator cuff syndrome? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Rotator cuff syndrome when taking Bydureon? *

  • female: 76.47 %
  • male: 23.53 %

What is the age of people who have Rotator cuff syndrome when taking Bydureon? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 33.33 %
  • 60+: 55.56 %

What are other drugs people take besides Bydureon? *

  1. Metformin: 7 people, 41.18%
  2. Baby Aspirin: 3 people, 17.65%
  3. Crestor: 3 people, 17.65%
  4. Fish Oil: 3 people, 17.65%
  5. Amlodipine: 2 people, 11.76%
  6. Glumetza: 2 people, 11.76%
  7. Levemir: 2 people, 11.76%
  8. Benicar: 2 people, 11.76%
  9. Bydureon Bcise: 2 people, 11.76%
  10. Byetta: 2 people, 11.76%

What are other side effects people have besides Rotator cuff syndrome? *

  1. Weight Decreased: 3 people, 17.65%
  2. Injection Site Extravasation (flow of (blood or lymph) from injection site): 3 people, 17.65%
  3. Injection Site Mass: 3 people, 17.65%
  4. Kidney Stones: 3 people, 17.65%
  5. Muscle Spasms (muscle contraction): 3 people, 17.65%
  6. Fall: 3 people, 17.65%
  7. Abdominal Discomfort: 2 people, 11.76%
  8. Constipation: 2 people, 11.76%
  9. Glycosylated Haemoglobin Increased: 2 people, 11.76%
  10. Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 11.76%

What are the existing conditions these people have? *

  1. Blood Pressure Abnormal: 5 people, 29.41%
  2. High Blood Cholesterol: 4 people, 23.53%
  3. Glycosylated Haemoglobin Increased: 3 people, 17.65%
  4. Cardiac Disorder: 3 people, 17.65%
  5. Renal Disorder (kidney disease): 2 people, 11.76%
  6. Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 5.88%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
  8. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 5.88%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.88%
  10. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Bydureon and have Rotator cuff syndrome?

- Check whether Rotator cuff syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bydureon:

Rotator cuff syndrome treatments and more:

How severe was Rotator cuff syndrome and when was it recovered:

Expand to all the drugs that have ingredients of exenatide synthetic:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bydureon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rotator cuff syndrome:

Browse all the conditions that are associated with Rotator cuff syndrome:


How the study uses the data?

The study uses data from the FDA. It is based on exenatide synthetic (the active ingredients of Bydureon) and Bydureon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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