Byetta and Choledocholithiasis - a phase IV clinical study of FDA data

Summary:

Choledocholithiasis is reported as a side effect among people who take Byetta (exenatide synthetic), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lantus, and have High blood pressure.

The phase IV clinical study analyzes which people have Choledocholithiasis when taking Byetta. It is created by eHealthMe based on reports of 60,421 people who have side effects when taking Byetta from the FDA, and is updated regularly.

What is Byetta?

Byetta has active ingredients of exenatide synthetic. It is often used in diabetes. eHealthMe is studying from 60,818 Byetta users. Check the latest studies of Byetta.

What is Choledocholithiasis?

Choledocholithiasis (stones in the common bile duct) is found to be associated with 607 drugs and 958 conditions by eHealthMe. Check the latest studies of Choledocholithiasis.



On Jul, 18, 2026

60,421 people reported to have side effects when taking Byetta.
Among them, 22 people (0.04%) have Choledocholithiasis.

Could Byetta cause Choledocholithiasis?

Among these 22 people:

How long have people been on Byetta when they have Choledocholithiasis? *

  • < 1 month: 6.25 %
  • 1 - 6 months: 37.5 %
  • 6 - 12 months: 18.75 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 37.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Choledocholithiasis when taking Byetta? *

  • female: 80.95 %
  • male: 19.05 %

What is the age of people who have Choledocholithiasis when taking Byetta? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.88 %
  • 30-39: 5.88 %
  • 40-49: 17.65 %
  • 50-59: 35.29 %
  • 60+: 35.29 %

What are other drugs people take besides Byetta? *

  1. Lantus: 5 people, 22.73%
  2. Vicodin: 4 people, 18.18%
  3. Levemir: 4 people, 18.18%
  4. Lotrel: 3 people, 13.64%
  5. Coreg: 3 people, 13.64%
  6. Coumadin: 3 people, 13.64%
  7. Crestor: 3 people, 13.64%
  8. Elavil: 3 people, 13.64%
  9. Glyburide: 3 people, 13.64%
  10. Lasix: 2 people, 9.09%

What are other side effects people have besides Choledocholithiasis? *

  1. Pancreatitis (inflammation of pancreas): 12 people, 54.55%
  2. Weight Decreased: 7 people, 31.82%
  3. Nausea (feeling of having an urge to vomit): 5 people, 22.73%
  4. Hepatic Steatosis (fatty liver disease): 4 people, 18.18%
  5. Abdominal Discomfort: 3 people, 13.64%
  6. Renal Injury (kidney injury): 3 people, 13.64%
  7. Gallstones (stone formation by bile component): 3 people, 13.64%
  8. Adenocarcinoma Pancreas (cancer of pancreas): 2 people, 9.09%
  9. Anaemia (lack of blood): 2 people, 9.09%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.09%

What are the existing conditions these people have? *

  1. High Blood Pressure: 4 people, 18.18%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.09%
  3. Cardiac Disorder: 2 people, 9.09%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 9.09%
  5. Weight Loss: 1 person, 4.55%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.55%
  7. High Blood Cholesterol: 1 person, 4.55%
  8. Depression: 1 person, 4.55%
  9. Birth Control: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Byetta and have Choledocholithiasis?

- Check whether Choledocholithiasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Byetta:

Choledocholithiasis treatments and more:

How severe was Choledocholithiasis and when was it recovered:

Expand to all the drugs that have ingredients of exenatide synthetic:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Byetta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Choledocholithiasis:

Browse all the conditions that are associated with Choledocholithiasis:


How the study uses the data?

The study uses data from the FDA. It is based on exenatide synthetic (the active ingredients of Byetta) and Byetta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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