Byetta and Sphincter of oddi dysfunction - a phase IV clinical study of FDA data

Summary:

Sphincter of oddi dysfunction is reported as a side effect among people who take Byetta (exenatide synthetic), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Lantus, and have High blood pressure.

The phase IV clinical study analyzes which people have Sphincter of oddi dysfunction when taking Byetta. It is created by eHealthMe based on reports of 60,421 people who have side effects when taking Byetta from the FDA, and is updated regularly.

What is Byetta?

Byetta has active ingredients of exenatide synthetic. It is often used in diabetes. eHealthMe is studying from 60,818 Byetta users. Check the latest studies of Byetta.

What is Sphincter of oddi dysfunction?

Sphincter of oddi dysfunction (dysfunction of a muscular valve that controls the flow of digestive juices) is found to be associated with 80 drugs and 219 conditions by eHealthMe. Check the latest studies of Sphincter of oddi dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

60,421 people reported to have side effects when taking Byetta.
Among them, 16 people (0.03%) have Sphincter of oddi dysfunction.

Could Byetta cause Sphincter of oddi dysfunction?

Among these 16 people:

How long have people been on Byetta when they have Sphincter of oddi dysfunction? *

What is the gender of people who have Sphincter of oddi dysfunction when taking Byetta? *

female: 100 %
male: 0.0 %

What is the age of people who have Sphincter of oddi dysfunction when taking Byetta? *

What are other drugs people take besides Byetta? *

What are other side effects people have besides Sphincter of oddi dysfunction? *

Bile Duct Stenosis (abnormal narrowing of the common bile duct): 11 people, 68.75%
Pancreatic Duct Stenosis (abnormal narrowing of a passage in the pancreatic duct): 11 people, 68.75%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 11 people, 68.75%
Chronic Hepatitis (long lasting inflammation of liver): 11 people, 68.75%
Pancreatitis Chronic (chronic inflammation of pancreas): 5 people, 31.25%
Hepatic Steatosis (fatty liver disease): 5 people, 31.25%
Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 5 people, 31.25%
Weight Decreased: 4 people, 25.00%
Portal Vein Phlebitis (inflammation of a hepatic portal vein): 2 people, 12.50%
Liver Function Test Abnormal: 2 people, 12.50%

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 87.50%
Asthma: 11 people, 68.75%
Sleep Apnea Syndrome: 11 people, 68.75%
Pain: 11 people, 68.75%
Osteopenia (a condition where bone mineral density is lower than normal): 11 people, 68.75%
Nausea (feeling of having an urge to vomit): 11 people, 68.75%
Muscle Spasms (muscle contraction): 11 people, 68.75%
Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 11 people, 68.75%
Itching: 11 people, 68.75%
Irritable Bowel Syndrome: 11 people, 68.75%

* Approximation only. Some reports may have incomplete information.

Do you take Byetta and have Sphincter of oddi dysfunction?

- Check whether Sphincter of oddi dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Byetta:

Byetta (60,818 reports)

Browse all side effects of Byetta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sphincter of oddi dysfunction:

Sphincter of oddi dysfunction (80 drugs)

Browse all the conditions that are associated with Sphincter of oddi dysfunction:

Sphincter of oddi dysfunction (219 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on exenatide synthetic (the active ingredients of Byetta) and Byetta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.