Bystolic and Interstitial nephritis - a phase IV clinical study of FDA data

Summary:

Interstitial nephritis is reported as a side effect among people who take Bystolic (nebivolol hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Interstitial nephritis when taking Bystolic. It is created by eHealthMe based on reports of 18,660 people who have side effects when taking Bystolic from the FDA, and is updated regularly.

What is Bystolic?

Bystolic has active ingredients of nebivolol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 20,662 Bystolic users. Check the latest studies of Bystolic.

What is Interstitial nephritis?

Interstitial nephritis (inflammation of the kidney) is found to be associated with 1,095 drugs and 1,565 conditions by eHealthMe. Check the latest studies of Interstitial nephritis.

On Jul, 13, 2026

18,660 people reported to have side effects when taking Bystolic.
Among them, 50 people (0.27%) have Interstitial nephritis.

Could Bystolic cause Interstitial nephritis?

Among these 50 people:

How long have people been on Bystolic when they have Interstitial nephritis? *

What is the gender of people who have Interstitial nephritis when taking Bystolic? *

female: 26.53 %
male: 73.47 %

What is the age of people who have Interstitial nephritis when taking Bystolic? *

What are other drugs people take besides Bystolic? *

What are other side effects people have besides Interstitial nephritis? *

Chronic Kidney Disease: 48 people, 96.00%
Acute Kidney Failure: 47 people, 94.00%
Nephrogenic Anaemia (anaemia due to kidney disease): 26 people, 52.00%
Renal Injury (kidney injury): 13 people, 26.00%
Renal Impairment (severely reduced kidney function): 10 people, 20.00%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 8 people, 16.00%
Indigestion: 6 people, 12.00%
Death: 5 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.00%
Renal Tubular Necrosis (death of kidney tubules): 4 people, 8.00%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 40 people, 80.00%
Pain: 25 people, 50.00%
High Blood Cholesterol: 23 people, 46.00%
Diabetes: 17 people, 34.00%
Stress And Anxiety: 13 people, 26.00%
Depression: 11 people, 22.00%
Gastric Ph Decreased: 9 people, 18.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 18.00%
Blood Pressure Abnormal: 9 people, 18.00%
Infection: 7 people, 14.00%

* Approximation only. Some reports may have incomplete information.

Do you take Bystolic and have Interstitial nephritis?

- Check whether Interstitial nephritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bystolic:

Bystolic (20,662 reports)

Browse all side effects of Bystolic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Interstitial nephritis:

Interstitial nephritis (1,095 drugs)

Browse all the conditions that are associated with Interstitial nephritis:

Interstitial nephritis (1,565 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nebivolol hydrochloride (the active ingredients of Bystolic) and Bystolic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.