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Calan and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Calan (verapamil hydrochloride), especially for people who are female, 60+ old, also take Celebrex, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Sciatica when taking Calan. It is created by eHealthMe based on reports of 3,791 people who have side effects when taking Calan from the FDA, and is updated regularly.

What is Calan?

Calan has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 3,916 Calan users. Check the latest studies of Calan.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,147 drugs and 1,426 conditions by eHealthMe. Check the latest studies of Sciatica.

On Dec, 18, 2025

3,791 people reported to have side effects when taking Calan.
Among them, 22 people (0.58%) have Sciatica.

Could Calan cause Sciatica?

Among these 22 people:

What is the gender of people who have Sciatica when taking Calan? *

  • female: 77.27 %
  • male: 22.73 %

What is the age of people who have Sciatica when taking Calan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 42.11 %
  • 50-59: 5.26 %
  • 60+: 52.63 %

What are other drugs people take besides Calan? *

  1. Celebrex: 13 people, 59.09%
  2. Premarin: 10 people, 45.45%
  3. Voltaren: 10 people, 45.45%
  4. Vicodin: 10 people, 45.45%
  5. Ultram: 10 people, 45.45%
  6. Synthroid: 10 people, 45.45%
  7. Vioxx: 9 people, 40.91%
  8. Zoloft: 9 people, 40.91%
  9. Lopressor: 7 people, 31.82%
  10. Percocet: 6 people, 27.27%

What are other side effects people have besides Sciatica? *

  1. Fall: 15 people, 68.18%
  2. Joint Pain: 11 people, 50.00%
  3. Dizziness: 10 people, 45.45%
  4. Headache (pain in head): 10 people, 45.45%
  5. Pain: 10 people, 45.45%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 40.91%
  7. Depression: 9 people, 40.91%
  8. Emotional Distress: 9 people, 40.91%
  9. Back Pain: 8 people, 36.36%
  10. Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 7 people, 31.82%

What are the existing conditions these people have? *

  1. Menopause (end of monthly cycles in women): 5 people, 22.73%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 22.73%
  3. Joint Pain: 4 people, 18.18%
  4. Nasopharyngitis (inflammation of the nasopharynx): 1 person, 4.55%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Calan and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Calan:

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of verapamil hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride (the active ingredients of Calan) and Calan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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