Calcium carbonate and Polyneuropathy - a phase IV clinical study of FDA data

Summary:

Polyneuropathy is reported as a side effect among people who take Calcium carbonate (calcium), especially for people who are female, 60+ old, also take Pantoprazole, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Polyneuropathy when taking Calcium carbonate. It is created by eHealthMe based on reports of 15,732 people who have side effects when taking Calcium carbonate from the FDA, and is updated regularly.

What is Calcium carbonate?

Calcium carbonate has active ingredients of calcium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 16,045 Calcium carbonate users. Check the latest studies of Calcium carbonate.

What is Polyneuropathy?

Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously) is found to be associated with 916 drugs and 944 conditions by eHealthMe. Check the latest studies of Polyneuropathy.



On Jul, 10, 2026

15,732 people reported to have side effects when taking Calcium carbonate.
Among them, 19 people (0.12%) have Polyneuropathy.

Could Calcium carbonate cause Polyneuropathy?

Among these 19 people:

What is the gender of people who have Polyneuropathy when taking Calcium carbonate? *

  • female: 78.95 %
  • male: 21.05 %

What is the age of people who have Polyneuropathy when taking Calcium carbonate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.56 %
  • 50-59: 0.0 %
  • 60+: 94.44 %

What are other drugs people take besides Calcium carbonate? *

  1. Gabapentin: 11 people, 57.89%
  2. Pantoprazole: 11 people, 57.89%
  3. Furosemide: 9 people, 47.37%
  4. Valsartan: 9 people, 47.37%
  5. Aspirin: 9 people, 47.37%
  6. Pregabalin: 9 people, 47.37%
  7. Vitamin D: 8 people, 42.11%
  8. Rosuvastatin Calcium: 4 people, 21.05%
  9. Polyethylene Glycol 3350: 4 people, 21.05%
  10. Magnesium Sulfate: 3 people, 15.79%

What are other side effects people have besides Polyneuropathy? *

  1. Weakness: 11 people, 57.89%
  2. Myositis (inflammation of the muscles): 9 people, 47.37%
  3. Anaemia (lack of blood): 5 people, 26.32%
  4. Oedema Peripheral (superficial swelling): 4 people, 21.05%
  5. Dyspnea (difficult or laboured breathing): 3 people, 15.79%
  6. Pleural Effusion (water on the lungs): 3 people, 15.79%
  7. Hypokalemia (low potassium): 3 people, 15.79%
  8. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 2 people, 10.53%
  9. Joint Swelling: 2 people, 10.53%
  10. Dyslipidaemia (abnormal amount of lipids): 2 people, 10.53%

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 11 people, 57.89%
  2. Stress And Anxiety: 4 people, 21.05%
  3. Diarrhea: 3 people, 15.79%
  4. High Blood Pressure: 3 people, 15.79%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 10.53%
  6. Back Pain: 2 people, 10.53%
  7. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 10.53%
  8. Insomnia (sleeplessness): 2 people, 10.53%
  9. Cardiac Failure: 2 people, 10.53%
  10. Multiple Myeloma (cancer of the plasma cells): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Calcium carbonate and have Polyneuropathy?

- Check whether Polyneuropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Calcium carbonate:

Polyneuropathy treatments and more:

How severe was Polyneuropathy and when was it recovered:

Expand to all the drugs that have ingredients of calcium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Calcium carbonate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Polyneuropathy:

Browse all the conditions that are associated with Polyneuropathy:


How the study uses the data?

The study uses data from the FDA. It is based on calcium (the active ingredients of Calcium carbonate) and Calcium carbonate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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