Cannabis and Splenomegaly - a phase IV clinical study of FDA data

Summary:

Splenomegaly is reported as a side effect among people who take Cannabis (marijuana), especially for people who are male, 60+ old, also take Humira, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Splenomegaly when taking Cannabis. It is created by eHealthMe based on reports of 12,664 people who have side effects when taking Cannabis from the FDA, and is updated regularly.

What is Cannabis?

Cannabis has active ingredients of marijuana. It is often used in stress and anxiety. eHealthMe is studying from 13,371 Cannabis users. Check the latest studies of Cannabis.

What is Splenomegaly?

Splenomegaly (enlargement of spleen) is found to be associated with 1,120 drugs and 1,477 conditions by eHealthMe. Check the latest studies of Splenomegaly.

On Jul, 13, 2026

12,664 people reported to have side effects when taking Cannabis.
Among them, 26 people (0.21%) have Splenomegaly.

Among these 26 people:

What is the gender of people who have Splenomegaly when taking Cannabis? *

female: 3.85 %
male: 96.15 %

What is the age of people who have Splenomegaly when taking Cannabis? *

What are other drugs people take besides Cannabis? *

Prevacid: 18 people, 69.23%
Humira: 18 people, 69.23%
Cimzia: 17 people, 65.38%
Taltz: 14 people, 53.85%
Gabapentin: 5 people, 19.23%
Lamotrigine: 5 people, 19.23%
Ibuprofen: 4 people, 15.38%
Lithium Carbonate: 3 people, 11.54%
Modafinil: 3 people, 11.54%
Benazepril Hydrochloride: 3 people, 11.54%

What are other side effects people have besides Splenomegaly? *

Hyperhidrosis (abnormally increased sweating): 21 people, 80.77%
Abdominal Distension: 21 people, 80.77%
Nausea And Vomiting: 20 people, 76.92%
Weight Decreased: 20 people, 76.92%
Hepatic Failure (liver failure): 19 people, 73.08%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 18 people, 69.23%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 18 people, 69.23%
Confusional State: 18 people, 69.23%
Retching (strong involuntary effort to vomit): 18 people, 69.23%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 18 people, 69.23%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 15.38%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 11.54%
Sleep Disorder: 2 people, 7.69%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 7.69%
Nightmares (unpleasant dreams): 2 people, 7.69%
Mood Swings (an extreme or rapid change in mood): 2 people, 7.69%
Depression: 2 people, 7.69%
Bipolar Disorder (mood disorder): 2 people, 7.69%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Cannabis and have Splenomegaly?

- Check whether Splenomegaly is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cannabis:

Cannabis (13,371 reports)

Splenomegaly treatments and more:

Splenomegaly (17,257 reports)

Browse all side effects of Cannabis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenomegaly:

Splenomegaly (1,120 drugs)

Browse all the conditions that are associated with Splenomegaly:

Splenomegaly (1,477 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on marijuana (the active ingredients of Cannabis) and Cannabis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.