Capecitabine and Osteosclerosis - a phase IV clinical study of FDA data

Summary:

Osteosclerosis is reported as a side effect among people who take Capecitabine (capecitabine), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Zometa, and have Breast cancer.

The phase IV clinical study analyzes which people have Osteosclerosis when taking Capecitabine. It is created by eHealthMe based on reports of 59,451 people who have side effects when taking Capecitabine from the FDA, and is updated regularly.

What is Capecitabine?

Capecitabine has active ingredients of capecitabine. eHealthMe is studying from 59,495 Capecitabine users. Check the latest studies of Capecitabine.

What is Osteosclerosis?

Osteosclerosis (an elevation in bone density) is found to be associated with 636 drugs and 399 conditions by eHealthMe. Check the latest studies of Osteosclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

59,451 people reported to have side effects when taking Capecitabine.
Among them, 47 people (0.08%) have Osteosclerosis.

Could Capecitabine cause Osteosclerosis?

Among these 47 people:

How long have people been on Capecitabine when they have Osteosclerosis? *

What is the gender of people who have Osteosclerosis when taking Capecitabine? *

female: 97.5 %
male: 2.5 %

What is the age of people who have Osteosclerosis when taking Capecitabine? *

What are other drugs people take besides Capecitabine? *

What are other side effects people have besides Osteosclerosis? *

Stress And Anxiety: 36 people, 76.60%
Metastases To Spine (cancer spreads to spine): 33 people, 70.21%
Metastases To Bone (cancer spreads to bone): 32 people, 68.09%
Dyspnea (difficult or laboured breathing): 31 people, 65.96%
Pain: 31 people, 65.96%
Weight Decreased: 30 people, 63.83%
Pleural Effusion (water on the lungs): 29 people, 61.70%
Pain In Jaw: 29 people, 61.70%
Emotional Distress: 29 people, 61.70%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 29 people, 61.70%

What are the existing conditions these people have? *

Breast Cancer: 20 people, 42.55%
Metastases To Bone (cancer spreads to bone): 10 people, 21.28%
Breast Cancer Metastatic: 9 people, 19.15%
Pain: 7 people, 14.89%
Multiple Myeloma (cancer of the plasma cells): 7 people, 14.89%
Insomnia (sleeplessness): 7 people, 14.89%
Trismus (reduced opening of the jaws): 6 people, 12.77%
Drug Dependence: 6 people, 12.77%
Diabetes: 5 people, 10.64%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Capecitabine and have Osteosclerosis?

- Check whether Osteosclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Capecitabine:

Capecitabine (59,495 reports)

Osteosclerosis treatments and more:

Osteosclerosis (2,741 reports)

Browse all side effects of Capecitabine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteosclerosis:

Osteosclerosis (636 drugs)

Browse all the conditions that are associated with Osteosclerosis:

Osteosclerosis (399 conditions)

Related publications that referenced our studies

Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .
Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on capecitabine (the active ingredients of Capecitabine) and Capecitabine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.